Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.49 |
| ▸ | DRD4 | P21917 | 4/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.49 |
| ▸ | PDE2A | O00408 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24460692 | 0.80 | PDE2A (0.52) | CNR2SIGMAR1DRD4TMEM97PDE2A | |
| SCHEMBL24460628 | 0.80 | ALDH1A1 (0.52) | CNR2SIGMAR1DRD4TMEM97PDE2A | |
| SCHEMBL24460697 | 0.75 | PDE2A (0.52) | CNR2SIGMAR1DRD4TMEM97PDE2A | |
| SCHEMBL12473618 | 0.72 | KDM1A (0.57) | DRD4TMEM97DRD2DRD3 | |
| SCHEMBL24460679 | 0.72 | DRD4 (0.52) | CNR2SIGMAR1DRD4TMEM97PDE2A | |
| SCHEMBL16215685 | 0.72 | SIGMAR1 (0.50) | SIGMAR1DRD4TMEM97PDE2AMEN1 | |
| SCHEMBL24460738 | 0.72 | PDE2A (0.48) | CNR2DRD4PDE2AMEN1KMT2A | |
| SCHEMBL24460625 | 0.71 | KDM4E (0.56) | CNR2PDE2AKDM4EMEN1KMT2A | |
| SCHEMBL24460661 | 0.71 | KDM4E (0.56) | CNR2PDE2AKDM4EMEN1KMT2A | |
| SCHEMBL17214558 | 0.70 | PDE2A (0.87) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109209-A1 | SMALL MOLECULE COMPOUNDS AND COMPOSITIONS | TELO THERAPEUTICS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |