Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD5 | P21918 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24460772 | 0.94 | ALDH1A1 (0.53) | ALDH1A1CNR2LMNAGAACYP1A2 | |
| SCHEMBL24460951 | 0.89 | ALDH1A1 (0.48) | ALDH1A1CNR2LMNAGAACYP1A2 | |
| SCHEMBL24460737 | 0.89 | ALDH1A1 (0.48) | ALDH1A1CNR2LMNAGAACYP1A2 | |
| SCHEMBL24460624 | 0.85 | GAA (0.58) | ALDH1A1CNR2GAACYP1A2CYP3A4 | |
| SCHEMBL9660685 | 0.84 | DRD2 (0.50) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL4275131 | 0.81 | ALDH1A1 (0.59) | ALDH1A1LMNAGAACYP1A2CYP3A4 | |
| SCHEMBL1955800 | 0.81 | ALDH1A1 (0.71) | ALDH1A1LMNAGAACYP1A2CYP3A4 | |
| SCHEMBL6189062 | 0.81 | ALDH1A1 (0.59) | ALDH1A1LMNAGAACYP1A2CYP3A4 | |
| SCHEMBL1547055 | 0.79 | DRD4 (0.72) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL1546881 | 0.79 | DRD4 (0.72) | DRD2DRD1DRD4DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109209-A1 | SMALL MOLECULE COMPOUNDS AND COMPOSITIONS | TELO THERAPEUTICS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |