SCHEMBL2446085

SCHEMBL2446085

COc1ccc(C(C)(C)C)cc1S(N)(=O)=O

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.57
CA9 Q16790 5/20 0.57
CA1 P00915 3/20 0.57
PKM P14618 2/20 0.57
ALDH1A1 P00352 3/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
KMT2A Q03164 1/20 0.52
ALPL P05186 1/20 0.50
WDR5 P61964 1/20 0.49
CA12 O43570 3/20 0.49
ATM Q13315 1/20 0.47
CA4 P22748 1/20 0.46
BRD4 O60885 1/20 0.44
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29469839 1.00 CA2 (0.57) CA2CA9CA1PKMALDH1A1
SCHEMBL21962105 0.88 PKM (0.59) CA2CA9CA1PKMALDH1A1
SCHEMBL10780912 0.86 CA1 (0.54) CA2CA9CA1PKMALDH1A1
SCHEMBL35406099 0.86 PKM (0.54) CA2CA9CA1PKMALDH1A1
SCHEMBL5189382 0.86 PKM (0.54) CA2CA9CA1PKMALDH1A1
SCHEMBL27856555 0.86 CA1 (0.57) CA2CA9CA1PKMALDH1A1
SCHEMBL10710253 0.84 SMN1; SMN2 (0.62) CA2CA9CA1ALDH1A1SMN1; SMN2
SCHEMBL8048512 0.83 PKM (0.51) CA2CA9CA1PKMALDH1A1
SCHEMBL28022375 0.83 PKM (0.55) CA2CA9CA1PKMALDH1A1
SCHEMBL31525849 0.82 PKM (0.50) CA2CA9CA1PKMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 464 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0170164-B1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1988-10-05 EP claimed
US-H122-H PYRAZOLOAZOLE-TYPE MAGENTA COUPLER DISPERSED IN A HIGH-BOILING PHOSPHATE SOLVENT FUJI PHOTO FILM CO., LTD. (JP) 1986-09-02 US claimed
EP-0170164-A2 Silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1986-02-05 EP claimed
EP-4229045-B1 SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER BROAD INST INC (US) 2025-11-12 EP disclosed
US-12357603-B2 Acyl sulfonamides for treating cancer BAYER AKTIENGESELLSCHAFT (DE) 2025-07-15 US disclosed
US-20240287048-A1 SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER BAYER AKTIENGESELLSCHAFT (DE) 2024-08-29 US disclosed
US-20240279207-A1 SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER BAYER AKTIENGESELLSCHAFT (DE) 2024-08-22 US disclosed
EP-4229045-A1 SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER The Broad Institute Inc. (US) 2023-08-23 EP disclosed
EP-4229048-A1 SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER The Broad Institute, Inc. (US) 2023-08-23 EP disclosed
EP-3959202-B1 ACYL SULFONAMIDES FOR TREATING CANCER BAYER AG (DE) 2023-08-16 EP disclosed
US-20220226279-A1 ACYL SULFONAMIDES FOR TREATING CANCER THE BROAD INSTITUTE, INC. 2022-07-21 US disclosed
EP-0170164-A2 Silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1986-02-05 EP disclosed
US-4559297-A DISCOLORATION INHIBITION FUJI PHOTO FILM CO., LTD. (JP) 1985-12-17 US disclosed
EP-0164130-A2 Silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1985-12-11 EP disclosed
US-4540654-A Method of forming color image comprising heterocyclic magenta dye-forming coupler FUJI PHOTO FILM CO., LTD. (JP) 1985-09-10 US disclosed
EP-0135860-A2 Derivatives of 6-sulfoxyphenol, their preparation and their use as cytoprotectors; use of derivatives of salicylaldehyde as cytoprotectors HOECHST AKTIENGESELLSCHAFT (DE) 1985-04-03 EP disclosed
US-4500630-A USING AN IMIDAZOLO(1,2-B)PYRAZOLE COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1985-02-19 US disclosed
EP-0119741-A2 Method of producing magenta images in silver halide colour photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1984-09-26 EP disclosed
EP-0119860-A2 Pyrazolo magenta couplers used in silver halide photography FUJI PHOTO FILM CO., LTD. (JP) 1984-09-26 EP disclosed
EP-0088345-A2 2-Aminomethyl-6-sulfamoylphenol derivatives, process for their preparation, their use and pharmaceutical preparations based on these compounds HOECHST AKTIENGESELLSCHAFT (DE) 1983-09-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240287048-A1 SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER KAT6A, KAT6B, KAT2A CA2 2985/4885CA9 2304/4885CA1 2072/4885
US-20220226279-A1 ACYL SULFONAMIDES FOR TREATING CANCER KAT6A, KAT6B, KAT2A CA2 2884/4885CA9 2045/4885CA1 1716/4885
US-12357603-B2 Acyl sulfonamides for treating cancer KAT6A, KAT6B, KAT2A CA2 2884/4885CA9 2045/4885CA1 1716/4885
US-20240279207-A1 SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER KAT6A, KAT6B, KAT2A CA2 2865/4885CA9 1575/4885CA1 1714/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.