SCHEMBL4342168

SCHEMBL4342168

C=CCN(CC=C)C(=O)C(O)C(O)C(=O)N(C(C)=O)C(C)=O

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
DPP4 P27487 1/20 0.36
POLB P06746 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2446348 0.86 ALDH1A1 (0.48) ALDH1A1DPP4POLBSMN1; SMN2
SCHEMBL6919191 0.86 ALDH1A1 (0.48) ALDH1A1DPP4POLBSMN1; SMN2
SCHEMBL2446346 0.79 ALDH1A1 (0.42) ALDH1A1DPP4POLBSMN1; SMN2
SCHEMBL612188 0.77 ALDH1A1 (0.41) ALDH1A1DPP4POLBSMN1; SMN2
SCHEMBL14521230 0.77 ALDH1A1 (0.41) ALDH1A1DPP4POLBSMN1; SMN2
SCHEMBL2187457 0.74 ALDH1A1 (0.45) ALDH1A1DPP4POLBSMN1; SMN2
SCHEMBL16191438 0.73 ALDH1A1 (0.37) ALDH1A1DPP4POLBSMN1; SMN2
Acrylamide SCHEMBL7521468 0.73 ALDH1A1 (0.39) ALDH1A1DPP4POLB
SCHEMBL7557602 0.73 TSHR (0.43) ALDH1A1POLBSMN1; SMN2
SCHEMBL173228 0.73 ALDH1A1 (0.52) ALDH1A1DPP4POLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7576034-B2 Crosslinked three-dimensional polymer network, method for preparing same, support material comprising same and uses thereof EKA CHEMICALS AB (SE) 2009-08-18 US claimed
EP-1606320-B1 CROSSLINKED THREE-DIMENSIONAL POLYMER NETWORK, METHOD FOR PREPARING SAME, SUPPORT MATERIAL COMPRISING SAME AND USES THEREOF CHIROSEP (FR) 2007-06-13 EP claimed
EP-1606320-A1 CROSSLINKED THREE-DIMENSIONAL POLYMER NETWORK, METHOD FOR PREPARING SAME, SUPPORT MATERIAL COMPRISING SAME AND USES THEREOF CHIROSEP (FR) 2005-12-21 EP claimed
US-20040265267-A1 Crosslinked three-dimensional polymer network, method for preparing same, support material comprising same and uses thereof CHIROSEP (FR) 2004-12-30 US claimed
US-20040260081-A1 Crosslinked three-dimensional polymer network, method for preparing same, support material comprising same and uses thereof EKA CHEMICALS AB (SE) 2004-12-23 US claimed
WO-2004085485-A1 CROSSLINKED THREE-DIMENSIONAL POLYMER NETWORK, METHOD FOR PREPARING SAME, SUPPORT MATERIAL COMPRISING SAME AND USES THEREOF CHIROSEP (FR) 2004-10-07 WO claimed
EP-1427525-A2 CROSSLINKED THREE-DIMENSIONAL POLYMER NETWORK, METHOD FOR PREPARING SAME, SUPPORT MATERIAL COMPRISING SAME AND USES THEREOF Chirosep (FR) 2004-06-16 EP claimed
WO-2003026793-A2 CROSSLINKED THREE-DIMENSIONAL POLYMER NETWORK, METHOD FOR PREPARING SAME, SUPPORT MATERIAL COMPRISING SAME AND USES THEREOF EKA CHEMICALS AB (SE) 2003-04-03 WO claimed
US-7576034-B2 Crosslinked three-dimensional polymer network, method for preparing same, support material comprising same and uses thereof EKA CHEMICALS AB (SE) 2009-08-18 US disclosed
EP-1606320-B1 CROSSLINKED THREE-DIMENSIONAL POLYMER NETWORK, METHOD FOR PREPARING SAME, SUPPORT MATERIAL COMPRISING SAME AND USES THEREOF CHIROSEP (FR) 2007-06-13 EP disclosed
EP-1606320-A1 CROSSLINKED THREE-DIMENSIONAL POLYMER NETWORK, METHOD FOR PREPARING SAME, SUPPORT MATERIAL COMPRISING SAME AND USES THEREOF CHIROSEP (FR) 2005-12-21 EP disclosed
US-20040265267-A1 Crosslinked three-dimensional polymer network, method for preparing same, support material comprising same and uses thereof CHIROSEP (FR) 2004-12-30 US disclosed
US-20040260081-A1 Crosslinked three-dimensional polymer network, method for preparing same, support material comprising same and uses thereof EKA CHEMICALS AB (SE) 2004-12-23 US disclosed
WO-2004085485-A1 CROSSLINKED THREE-DIMENSIONAL POLYMER NETWORK, METHOD FOR PREPARING SAME, SUPPORT MATERIAL COMPRISING SAME AND USES THEREOF CHIROSEP (FR) 2004-10-07 WO disclosed
EP-1427525-A2 CROSSLINKED THREE-DIMENSIONAL POLYMER NETWORK, METHOD FOR PREPARING SAME, SUPPORT MATERIAL COMPRISING SAME AND USES THEREOF Chirosep (FR) 2004-06-16 EP disclosed
WO-2003026793-A2 CROSSLINKED THREE-DIMENSIONAL POLYMER NETWORK, METHOD FOR PREPARING SAME, SUPPORT MATERIAL COMPRISING SAME AND USES THEREOF EKA CHEMICALS AB (SE) 2003-04-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040265267-A1 Crosslinked three-dimensional polymer network, method for preparing same, support material comprising same and uses thereof UROD, ALG1, NOTUM ALDH1A1 1294/4885DPP4 4238/4885POLB 3777/4885
US-20040260081-A1 Crosslinked three-dimensional polymer network, method for preparing same, support material comprising same and uses thereof MTCL3, OR10J3, MCM4 ALDH1A1 2168/4885DPP4 4475/4885POLB 3902/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.