SCHEMBL2446409

SCHEMBL2446409

O=C(O)/C=C/c1ccc(OCC2CO2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
THRB P10828 1/20 0.51
ATM Q13315 1/20 0.51
ALDH1A1 P00352 3/20 0.51
PKM P14618 3/20 0.51
LMNA P02545 1/20 0.51
GAA P10253 1/20 0.51
TP53 P04637 3/20 0.48
TSHR P16473 3/20 0.48
MAPT P10636 2/20 0.48
HPGD P15428 2/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
HIF1A Q16665 2/20 0.48
CYP1A2 P05177 1/20 0.48
PPARG P37231 1/20 0.48
PARP1 P09874 1/20 0.47
P4HTM Q9NXG6 1/20 0.45
TBXAS1 P24557 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2446412 1.00 MGLL (0.54) MGLLTDP1THRBATMALDH1A1
SCHEMBL9513254 0.90 ALDH1A1 (0.53) MGLLTDP1ALDH1A1PKMLMNA
SCHEMBL9513259 0.90 ALDH1A1 (0.53) MGLLTDP1ALDH1A1PKMLMNA
SCHEMBL10353006 0.90 ALDH1A1 (0.53) MGLLTDP1ALDH1A1PKMLMNA
SCHEMBL2477789 0.89 MGLL (0.49) MGLLTHRBATMLMNAHPGD
SCHEMBL2477791 0.89 MGLL (0.49) MGLLTHRBATMLMNAHPGD
SCHEMBL10704074 0.87 TDP1 (0.58) MGLLTDP1ALDH1A1PKMLMNA
SCHEMBL10704069 0.87 TDP1 (0.58) MGLLTDP1ALDH1A1PKMLMNA
SCHEMBL10703802 0.86 MAOB (0.56) LMNAMAPTKMT2A
SCHEMBL10705357 0.86 MAOB (0.56) LMNAMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1945737-B1 COPOLYMER FOR LIQUID CRYSTAL ALIGNMENT, LIQUID CRYSTAL ALIGNING LAYER INCLUDING COPOLYMER FOR LIQUID CRYSTAL ALIGNMENT, AND LIQUID CRYSTAL DISPLAY INCLUDING LIQUID CRYSTAL ALIGNING LAYER LG CHEMICAL LTD (KR) 2013-03-06 EP disclosed
EP-1422255-B1 MAIN CHAIN TYPE LIQUID CRYSTAL POLYESTER LIQUID CRYSTALLINE COMPOSITION METHOD FOR PRODUCING LIQUID CRYSTAL FILM OPTICAL FILM AND DISPLAY NIPPON OIL CORP (JP) 2011-09-28 EP disclosed
US-20100208182-A1 METHOD FOR MANUFACTURING OPTICAL FILM NIPPON OIL CORPORATION (JP) 2010-08-19 US disclosed
EP-2202546-A1 METHOD FOR PRODUCING OPTICAL FILM Nippon Oil Corporation (JP) 2010-06-30 EP disclosed
EP-1945737-A1 COPOLYMER FOR LIQUID CRYSTAL ALIGNMENT, LIQUID CRYSTAL ALIGNING LAYER INCLUDING COPOLYMER FOR LIQUID CRYSTAL ALIGNMENT, AND LIQUID CRYSTAL DISPLAY INCLUDING LIQUID CRYSTAL ALIGNING LAYER LG Chem, Ltd. (KR) 2008-07-23 EP disclosed
WO-2007052979-A1 COPOLYMER FOR LIQUID CRYSTAL ALIGNMENT, LIQUID CRYSTAL ALIGNING LAYER INCLUDING COPOLYMER FOR LIQUID CRYSTAL ALIGNMENT, AND LIQUID CRYSTAL DISPLAY INCLUDING LIQUID CRYSTAL ALIGNING LAYER LG CHEM. LTD. (KR) 2007-05-10 WO disclosed
US-6894141-B2 Main chain type liquid crystalline polyester, liquid crystalline composition, method for producing liquid crystal film and optical film, and display having optical film NIPPON OIL CORPORATION (JP) 2005-05-17 US disclosed
US-20040171788-A1 Main chain type liquid crystal polyester, liquid crystalline composition, method for producing liquid crystal film, optical film and display NOBLE VENTURE FINANCE I LIMITED (GB) 2004-09-02 US disclosed
EP-1422255-A1 MAIN CHAIN TYPE LIQUID CRYSTAL POLYESTER LIQUID CRYSTALLINE COMPOSITION METHOD FOR PRODUCING LIQUID CRYSTAL FILM OPTICAL FILM AND DISPLAY Nippon Oil Corporation (JP) 2004-05-26 EP disclosed