Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | WDR91 | A4D1P6 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2449553 | 0.85 | MTNR1A (0.51) | SMN1; SMN2MAPTGFERKMT2AKDM2B | |
| SCHEMBL2448228 | 0.84 | WDR91 (0.51) | RAB9ANPC1ALDH1A1WDR91SMN1; SMN2 | |
| SCHEMBL79756 | 0.82 | WDR91 (0.52) | RAB9ANPC1ALDH1A1WDR91POLB | |
| SCHEMBL8125365 | 0.82 | ALDH1A1 (0.60) | RAB9ANPC1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL2449550 | 0.81 | NOTUM (0.61) | RAB9ANPC1ALDH1A1WDR91MAPT | |
| SCHEMBL2451481 | 0.81 | WDR91 (0.66) | WDR91KMT2AL3MBTL1PRKDC | |
| SCHEMBL2446475 | 0.81 | KMT2A (0.62) | ALDH1A1WDR91SMN1; SMN2MAPTKMT2A | |
| SCHEMBL10207986 | 0.81 | ZAP70 (0.49) | RAB9AALDH1A1WDR91SMN1; SMN2KDM4E | |
| SCHEMBL1911872 | 0.81 | ZAP70 (0.49) | ALDH1A1SMN1; SMN2MAPTKDM4EPRKDC | |
| SCHEMBL12311809 | 0.81 | ZAP70 (0.49) | RAB9AALDH1A1WDR91SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2362775-A1 | CHEMICAL COMPOUNDS | GlaxoSmithKline LLC (US) | 2011-09-07 | — | — | EP | disclosed |