Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | AHCY | P23526 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.45 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.44 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.44 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.44 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21374101 | 1.00 | ALDH1A1 (0.56) | ALDH1A1HIF1AAHCYADORA1P2RY1 | |
| SCHEMBL20769872 | 0.93 | ALDH1A1 (0.58) | ALDH1A1HIF1AAHCYADORA1P2RY1 | |
| SCHEMBL21859151 | 0.86 | ADORA1 (0.50) | AHCYADORA1P2RY1P2RY2SRC | |
| SCHEMBL6762689 | 0.86 | ADORA1 (0.50) | AHCYADORA1P2RY1P2RY2SRC | |
| SCHEMBL30867101 | 0.86 | ADORA1 (0.50) | AHCYADORA1P2RY1P2RY2SRC | |
| SCHEMBL22220143 | 0.86 | ADORA1 (0.50) | AHCYADORA1P2RY1P2RY2SRC | |
| SCHEMBL21859282 | 0.86 | ADORA1 (0.50) | AHCYADORA1P2RY1P2RY2SRC | |
| SCHEMBL14565266 | 0.85 | ADORA1 (0.49) | AHCYADORA1P2RY1P2RY2SRC | |
| SCHEMBL23025557 | 0.85 | ADORA3 (0.51) | AHCYADORA1P2RY1P2RY2SRC | |
| SCHEMBL23002345 | 0.84 | ADORA1 (0.57) | ADORA1P2RY1P2RY2SRCSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3573718-B1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | JANSSEN BIOTECH INC (US) | 2022-06-01 | — | — | EP | disclosed |