Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | AHCY | P23526 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.45 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.44 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.44 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.44 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24465182 | 1.00 | ALDH1A1 (0.56) | ALDH1A1HIF1AAHCYADORA1P2RY1 | |
| SCHEMBL20769872 | 0.93 | ALDH1A1 (0.58) | ALDH1A1HIF1AAHCYADORA1P2RY1 | |
| SCHEMBL21859151 | 0.86 | ADORA1 (0.50) | AHCYADORA1P2RY1P2RY2SRC | |
| SCHEMBL6762689 | 0.86 | ADORA1 (0.50) | AHCYADORA1P2RY1P2RY2SRC | |
| SCHEMBL30867101 | 0.86 | ADORA1 (0.50) | AHCYADORA1P2RY1P2RY2SRC | |
| SCHEMBL22220143 | 0.86 | ADORA1 (0.50) | AHCYADORA1P2RY1P2RY2SRC | |
| SCHEMBL21859282 | 0.86 | ADORA1 (0.50) | AHCYADORA1P2RY1P2RY2SRC | |
| SCHEMBL14565266 | 0.85 | ADORA1 (0.49) | AHCYADORA1P2RY1P2RY2SRC | |
| SCHEMBL23025557 | 0.85 | ADORA3 (0.51) | AHCYADORA1P2RY1P2RY2SRC | |
| SCHEMBL23002345 | 0.84 | ADORA1 (0.57) | ADORA1P2RY1P2RY2SRCSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210054015-A1 | 3'',5''-DIMETHOXYBENZOYL-3'-AMINO-3'-DEOXYADENOSINE-5'-TRIPHOSPHATES AND PHARMACEUTICAL USES THEREOF | DANMIR THERAPEUTICS, LLC | 2021-02-25 | — | — | US | disclosed |
| WO-2019178331-A1 | 3\",5\"-DIALKOXYBENZOYL-3'-AMINO-3'-DEOXYADENOSINE-5'-TRIPHOSPHATES AND PHARMACEUTICAL USES THEREOF | DANMIR THERAPEUTICS, LLC (US) | 2019-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210054015-A1 | 3'',5''-DIMETHOXYBENZOYL-3'-AMINO-3'-DEOXYADENOSINE-5'-TRIPHOSPHATES AND PHARMACEUTICAL USES THEREOF | P2RX3, ADORA3, P2RX6 | ALDH1A1 1601/4885HIF1A 2152/4885AHCY 383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.