Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 2/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13267958 | 0.87 | LMNA (0.44) | LMNAHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL778073 | 0.81 | ACP3 (0.46) | GAASLC6A2SLC6A4SLC6A3SMN1; SMN2 | |
| SCHEMBL19041216 | 0.80 | KMT2A (0.42) | LMNAHSD17B10MEN1KMT2ASLC6A2 | |
| SCHEMBL1878466 | 0.79 | SLC6A2 (0.48) | HSD17B10ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL50454 | 0.78 | LMNA (0.80) | LMNAHSD17B10ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL15105762 | 0.78 | L3MBTL1 (0.56) | HSD17B10ALDH1A1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL4935067 | 0.77 | LMNA (0.61) | LMNAHSD17B10ALDH1A1GAAMEN1 | |
| SCHEMBL10446352 | 0.77 | SLC6A2 (0.49) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL3647676 | 0.77 | LMNA (0.77) | LMNAHSD17B10ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL387303 | 0.77 | LMNA (0.57) | LMNAHSD17B10ALDH1A1KMT2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4005567-A1 | ISOFLAVONOID COMPOSITION WITH IMPROVED PHARMACOKINETICS | Noxopharm Limited (AU) | 2022-06-01 | — | — | EP | disclosed |