Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9482041 | 0.84 | LMNA (0.48) | CACNA1HLMNAALDH1A1SIGMAR1CNR1 | |
| SCHEMBL17662438 | 0.81 | FAAH (0.44) | RECQLCACNA1HGAALMNAALDH1A1 | |
| SCHEMBL17914454 | 0.81 | RECQL (0.42) | RECQLCACNA1HGAAALDH1A1SIGMAR1 | |
| SCHEMBL11433061 | 0.80 | RECQL (0.40) | RECQLCACNA1HGAAALDH1A1SIGMAR1 | |
| SCHEMBL23798940 | 0.79 | FFAR1 (0.31) | ALDH1A1 | |
| SCHEMBL19176775 | 0.78 | HPGD (0.42) | RECQLGAALMNAHDAC4ALDH1A1 | |
| SCHEMBL20096362 | 0.78 | CACNA1H (0.40) | RECQLCACNA1HGAAALDH1A1SIGMAR1 | |
| SCHEMBL10730053 | 0.78 | ALDH1A1 (0.46) | RECQLCACNA1HGAAALDH1A1SIGMAR1 | |
| SCHEMBL20206734 | 0.77 | CYP2D6 (0.41) | RECQLMLYCDPSMB5 | |
| SCHEMBL19176866 | 0.76 | CNR1 (0.32) | ALDH1A1SIGMAR1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4006028-A1 | IRAK4 KINASE INHIBITOR AND PREPARATION METHOD THEREFOR | Zhuhai Yufan Biotechnologies Co., Ltd (CN) | 2022-06-01 | — | — | EP | disclosed |