SCHEMBL19981228

SCHEMBL19981228

Cn1cncc1-c1ccc(OC(F)(F)F)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATP1A1 P05023 1/20 0.45
ATP1B1 P05026 1/20 0.45
ATP1A3 P13637 1/20 0.45
ATP1B2 P14415 1/20 0.45
ATP1A2 P50993 1/20 0.45
ATP1B3 P54709 1/20 0.45
FXYD2 P54710 1/20 0.45
ATP1A4 Q13733 1/20 0.45
SCN5A Q14524 8/20 0.44
SCN10A Q9Y5Y9 5/20 0.44
KCNH2 Q12809 2/20 0.44
SCN1A P35498 1/20 0.44
SCN9A Q15858 1/20 0.44
SCN2A Q99250 1/20 0.44
SCN8A Q9UQD0 1/20 0.44
HPGDS O60760 1/20 0.44
IDO1 P14902 1/20 0.44
HTR1A P08908 1/20 0.42
HTR7 P34969 1/20 0.42
HTR6 P50406 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24465876 0.81 MAPT (0.51) HPGDSIDO1LDLRPCSK9GSK3B
SCHEMBL30948515 0.80 FNTB (0.45) SCN5AGSK3BDYRK1AFNTAFNTB
SCHEMBL19016861 0.79 KIF11 (0.47) HPGDSIDO1LDLRPCSK9GSK3B
SCHEMBL27398874 0.77 IDO1 (0.50) HPGDSIDO1HTR1AHTR7HTR6
SCHEMBL13589293 0.77 IDO1 (0.44) HPGDSIDO1HTR1AHTR7HTR6
SCHEMBL27933810 0.76 NPY5R (0.48) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL1502339 0.74 IDO1 (0.51) HPGDSIDO1HTR6LDLRPCSK9
SCHEMBL24460261 0.74 ATP1A1 (0.55) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL6290646 0.74 PTGS2 (0.64) IDO1
SCHEMBL27915398 0.74 BCHE (0.48) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037326-B2 Diaryl-azole compound and formulation for controlling harmful organism NIPPON SODA CO., LTD. (JP) 2024-07-16 US disclosed
US-12037326-B2 Diaryl-azole compound and formulation for controlling harmful organism NIPPON SODA CO., LTD. (JP) 2024-07-16 US disclosed
US-12037326-B2 Diaryl-azole compound and formulation for controlling harmful organism NIPPON SODA CO., LTD. (JP) 2024-07-16 US disclosed
WO-2024034565-A1 IMIDAZOLYLAZOLE COMPOUND AND PEST CONTROL AGENT 日本曹達株式会社 2024-02-15 WO disclosed
CN-109689630-B Diaryl azole compound and pest control agent 日本曹达株式会社 2022-06-03 CN disclosed
EP-3514146-B1 DIARYL- AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM NIPPON SODA CO (JP) 2022-03-16 EP disclosed
US-20220033384-A1 DIARYL-AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM NIPPON SODA CO., LTD. (JP) 2022-02-03 US disclosed
US-20220033384-A1 DIARYL-AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM NIPPON SODA CO., LTD. (JP) 2022-02-03 US disclosed
US-11180485-B2 Diaryl-azole compound and formulation for controlling harmful organism NIPPON SODA CO., LTD. (JP) 2021-11-23 US disclosed
US-11180485-B2 Diaryl-azole compound and formulation for controlling harmful organism NIPPON SODA CO., LTD. (JP) 2021-11-23 US disclosed
EP-3514146-A1 DIARYL AZOLE COMPOUND AND PESTICIDE Nippon Soda Co., Ltd. (JP) 2019-07-24 EP disclosed
EP-3514146-A1 DIARYL AZOLE COMPOUND AND PESTICIDE Nippon Soda Co., Ltd. (JP) 2019-07-24 EP disclosed
US-20190185459-A1 DIARYL-AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM NIPPON SODA CO., LTD. (JP) 2019-06-20 US disclosed
US-20190185459-A1 DIARYL-AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM NIPPON SODA CO., LTD. (JP) 2019-06-20 US disclosed
CN-109689630-A Diaryl azole compound and pest control agent 日本曹达株式会社 2019-04-26 CN disclosed
WO-2018052035-A1 DIARYL AZOLE COMPOUND AND PESTICIDE 日本曹達株式会社 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220033384-A1 DIARYL-AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM CRY1, CRKL, CDC5L ATP1A1 470/4885ATP1B1 332/4885ATP1A3 569/4885
US-20190185459-A1 DIARYL-AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM CRY1, CRKL, CDC5L ATP1A1 470/4885ATP1B1 332/4885ATP1A3 569/4885
US-12037326-B2 Diaryl-azole compound and formulation for controlling harmful organism CRY1, CRKL, CDC5L ATP1A1 470/4885ATP1B1 332/4885ATP1A3 569/4885
US-11180485-B2 Diaryl-azole compound and formulation for controlling harmful organism CRY1, CRKL, CDC5L ATP1A1 470/4885ATP1B1 332/4885ATP1A3 569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.