Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20873280 | 0.79 | PPP5C (0.44) | TSHR | |
| SCHEMBL31759010 | 0.76 | L3MBTL1 (0.39) | RECQLSMN1; SMN2CA12CA1CA9 | |
| SCHEMBL20873337 | 0.75 | HRH3 (0.40) | — | |
| SCHEMBL20873245 | 0.75 | HRH3 (0.40) | RECQL | |
| SCHEMBL20873261 | 0.75 | HSD11B1 (0.47) | SMN1; SMN2KMT2A | |
| SCHEMBL20873300 | 0.74 | TFPI2 (0.54) | TSHRMEN1TP53KMT2AUSP2 | |
| SCHEMBL20873262 | 0.73 | HRH3 (0.42) | RECQLKMT2AALDH1A1L3MBTL1POLB | |
| SCHEMBL20873279 | 0.73 | HRH3 (0.50) | TSHRALDH1A1POLB | |
| SCHEMBL20873323 | 0.72 | RAB9A (0.36) | MEN1KMT2A | |
| SCHEMBL11158442 | 0.67 | TSHR (0.65) | RECQLSMN1; SMN2CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4006017-A1 | SGLT2/DPP4 INHIBITOR AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2022-06-01 | — | — | EP | disclosed |