Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.48 |
| ▸ | ACACB | O00763 | 9/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24945622 | 0.87 | GPR119 (0.50) | GPR119 | |
| SCHEMBL24467795 | 0.86 | GPR119 (0.55) | GPR119ACACB | |
| SCHEMBL24467778 | 0.86 | GPR119 (0.47) | GPR119ACACB | |
| SCHEMBL23744164 | 0.85 | GPR119 (0.46) | GPR119 | |
| SCHEMBL22048911 | 0.84 | GPR119 (0.45) | GPR119 | |
| SCHEMBL31027274 | 0.84 | CHRM2 (0.46) | GPR119ACACB | |
| SCHEMBL24945726 | 0.84 | GPR119 (0.45) | GPR119 | |
| SCHEMBL23744064 | 0.81 | GPR119 (0.44) | GPR119 | |
| SCHEMBL24945647 | 0.81 | GPR119 (0.46) | GPR119 | |
| SCHEMBL29165913 | 0.81 | ACACB (0.47) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157396-A | Pyridazinone derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| WO-2022111700-A1 | PYRIDAZINONE DERIVATIVES AND USE THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2022-06-02 | — | — | WO | disclosed |