Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 16/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23744164 | 0.89 | GPR119 (0.46) | GPR119HDAC1 | |
| SCHEMBL24945622 | 0.86 | GPR119 (0.50) | GPR119 | |
| SCHEMBL23744064 | 0.85 | GPR119 (0.44) | GPR119HDAC1MAPT | |
| SCHEMBL24467778 | 0.85 | GPR119 (0.47) | GPR119MAPT | |
| SCHEMBL24467779 | 0.84 | GPR119 (0.48) | GPR119 | |
| SCHEMBL31027274 | 0.82 | CHRM2 (0.46) | GPR119 | |
| SCHEMBL24945726 | 0.82 | GPR119 (0.45) | GPR119MAPT | |
| SCHEMBL24945647 | 0.81 | GPR119 (0.46) | GPR119MAPT | |
| SCHEMBL22048425 | 0.80 | GPR119 (0.59) | GPR119HDAC1MAP4K4MAPT | |
| SCHEMBL23560751 | 0.78 | MET (0.43) | GPR119HDAC1MAP4K4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11834432-B2 | Substituted amino six-membered nitric heterocyclic ring compound and preparation and use thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2023-12-05 | — | — | US | disclosed |
| US-11834432-B2 | Substituted amino six-membered nitric heterocyclic ring compound and preparation and use thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2023-12-05 | — | — | US | disclosed |
| EP-3418277-B1 | SUBSTITUTED AMINO SIX-MEMBERED NITRIC HETEROCYCLIC RING COMPOUND AND PREPARATION AND USE THEREOF | SHANGHAI INST MATERIA MEDICA CAS (CN) | 2020-10-14 | — | — | EP | disclosed |
| US-20200172510-A1 | SUBSTITUTED AMINO SIX-MEMBERED NITRIC HETEROCLIC RING COMPOUND AND PREPARATION AND USE THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2020-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172510-A1 | SUBSTITUTED AMINO SIX-MEMBERED NITRIC HETEROCLIC RING COMPOUND AND PREPARATION AND USE THEREOF | NOS2, NOS1, NOS3 | GPR119 397/4885HDAC1 2570/4885MAP4K4 130/4885 |
| US-11834432-B2 | Substituted amino six-membered nitric heterocyclic ring compound and preparation and use thereof | NOS2, NOS1, NOS3 | GPR119 427/4885HDAC1 2563/4885MAP4K4 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.