Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10426403 | 0.88 | THRB (0.57) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7121709 | 0.86 | THRB (0.52) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL29082867 | 0.82 | TSHR (0.71) | TSHRTHRBPOLBAPEX1HTT | |
| 1,4-Butanediol SCHEMBL3252686 | 0.82 | THRB (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL15480 | 0.82 | TSHR (0.64) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2505517 | 0.81 | THRB (0.52) | TSHRTHRBPOLBAPEX1HTT | |
| Water SCHEMBL7119412 | 0.80 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| 1,3-Propanediol SCHEMBL14910937 | 0.80 | TSHR (0.57) | TSHRTHRBPOLBAPEX1HTT | |
| Hydrochloric Acid SCHEMBL8398425 | 0.80 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL14872 | 0.80 | TSHR (0.68) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367618-A1 | MICROSPHERES | Akzo Nobel N.V. (NL) | 2011-09-28 | — | — | EP | disclosed |
| WO-2010072663-A1 | MICROSPHERES | AKZO NOBEL N.V. (NL) | 2010-07-01 | — | — | WO | disclosed |