Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2051132 | 0.90 | THRB (0.48) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL7121709 | 0.89 | THRB (0.52) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL31340001 | 0.88 | THRB (0.47) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL2446911 | 0.88 | TSHR (0.50) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL608159 | 0.87 | THRB (0.50) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL2453478 | 0.86 | THRB (0.57) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL587661 | 0.86 | THRB (0.57) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL9312977 | 0.86 | THRB (0.57) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL8751763 | 0.86 | THRB (0.48) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL29082867 | 0.85 | TSHR (0.71) | THRBTSHRALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4890911-A | Contact lens and the method of manufacturing thereof | CESKOSLOVENSKA AKADEMIE VED (CS) | 1990-01-02 | — | — | US | disclosed |