SCHEMBL7121709

SCHEMBL7121709

C=C(C)C(=O)OCCC(=O)CO

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.52
TSHR P16473 3/20 0.50
ALDH1A1 P00352 2/20 0.40
POLB P06746 1/20 0.38
APEX1 P27695 1/20 0.38
HTT P42858 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
EPHX1 P07099 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10426403 0.89 THRB (0.57) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL2446911 0.86 TSHR (0.50) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL5368442 0.83 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL608159 0.82 THRB (0.50) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL9312977 0.80 THRB (0.57) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL2453478 0.80 THRB (0.57) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL587661 0.80 THRB (0.57) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL8751763 0.80 THRB (0.48) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL2051132 0.80 THRB (0.48) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL29082867 0.80 TSHR (0.71) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140162294-A1 METHODS AND COMPOSITIONS FOR ASSAYING VITAMIN D GENERAL ATOMICS (US) 2014-06-12 US claimed
WO-2003028739-A2 COMPOSITION FOR PREVENTING OR TREATING HYPERLIPIDEMIA OR HYPERGLYCEMIA COMPRISING A POLYMER OR ITS SALT FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2003-04-10 WO claimed
JP-3291219-A None JP disclosed
JP-4194016-A None JP disclosed
JP-5043634-A None JP disclosed
JP-4117276-A None JP disclosed
US-20240176162-A1 EYEGLASS LENS HOYA LENS THAILAND LTD. (TH) 2024-05-30 US disclosed
CN-117203569-A Spectacle lens 豪雅镜片泰国有限公司 2023-12-08 CN disclosed
US-11767349-B2 Modified streptolysin O TOYOBO CO., LTD. (JP) 2023-09-26 US disclosed
WO-2023048107-A1 HARD COAT FILM 日本製紙株式会社 2023-03-30 WO disclosed
US-20220137264-A1 POLARIZING LENS AND METHOD FOR MANUFACTURING THE SAME HOYA LENS THAILAND LTD. (TH) 2022-05-05 US disclosed
US-6548310-B1 For detection of antigens, antibodies, enzymes, and nucleic acids; storage stability; calibration curves based on absorbance JSR CORPORATION (JP) 2003-04-15 US disclosed
US-6541587-B1 Saccharide-derived monomer, method for manufacturing the same and highly-dielectric polymer consisting of the said monomer JAPAN EXLAN COMPANY LIMITED (JP) 2003-04-01 US disclosed
US-20020127262-A1 Method for preparing hydroxyapatite composite and biocompatible material NOF CORPORATION AND MITSURU AKASHI 2002-09-12 US disclosed
US-6387414-B1 Method for preparing hydroxyapatite composite and biocompatible material NOF CORPORATION (JP) 2002-05-14 US disclosed
US-5747468-A Cationic unsaturated saccharides and polymers prepared therefrom, and their use HOECHST AKTIENGESELLSCHAFT (DE) 1998-05-05 US disclosed
JP-H0543634-A GRAFT POLYMER TAKEDA CHEM IND LTD 1993-02-23 JP disclosed
JP-H04194016-A GLYCOSIDE FIBER TEIJIN LTD 1992-07-14 JP disclosed
JP-H04117276-A DEVICE FOR MICROBE CULTURE MEDIUM SEKISUI CHEM CO LTD 1992-04-17 JP disclosed
JP-H03291219-A NEW PATCH AGENT FOR EXTERNAL USE AND PRODUCTION THEREOF HISAMITSU PHARMACEUT CO INC 1991-12-20 JP disclosed