Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20782935 | 0.93 | ALDH1A1 (0.60) | ALDH1A1EPHX1HIF1ACYP3A4 | |
| SCHEMBL150431 | 0.89 | ALDH1A1 (0.74) | ALDH1A1EPHX1HIF1ACYP3A4 | |
| SCHEMBL26028516 | 0.88 | ALDH1A1 (0.89) | ALDH1A1EPHX1HIF1ACYP3A4 | |
| SCHEMBL13194400 | 0.88 | ALDH1A1 (0.89) | ALDH1A1EPHX1HIF1ACYP3A4 | |
| SCHEMBL17875142 | 0.85 | ALDH1A1 (0.84) | ALDH1A1EPHX1HIF1ACYP3A4 | |
| SCHEMBL540664 | 0.85 | — | — | |
| SCHEMBL18709162 | 0.85 | ALDH1A1 (0.94) | ALDH1A1EPHX1HIF1ACYP3A4 | |
| SCHEMBL14523885 | 0.85 | ALDH1A1 (0.83) | ALDH1A1EPHX1HIF1ACYP3A4 | |
| SCHEMBL6196 | 0.85 | — | — | |
| SCHEMBL896571 | 0.84 | ALDH1A1 (0.54) | ALDH1A1EPHX1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220169605-A1 | NOVEL SUBSTITUTED SULFONYLUREA DERIVATIVES | ZYDUS LIFESCIENCES LIMITED (IN) | 2022-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220169605-A1 | NOVEL SUBSTITUTED SULFONYLUREA DERIVATIVES | NOD1, NLRP3, IL1R1 | ALDH1A1 347/4885EPHX1 1117/4885HIF1A 906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.