Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 20/20 | 0.46 |
| ▸ | SUZ12 | Q15022 | 15/20 | 0.44 |
| ▸ | EZH2 | Q15910 | 15/20 | 0.44 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24469482 | 0.81 | CYP3A4 (0.50) | EEDSUZ12EZH2 | |
| SCHEMBL21667264 | 0.79 | CYP3A4 (0.51) | — | |
| SCHEMBL24469533 | 0.78 | ALDH1A1 (0.46) | — | |
| SCHEMBL21667339 | 0.73 | CYP3A4 (0.46) | — | |
| SCHEMBL21667369 | 0.72 | ALDH1A1 (0.64) | — | |
| SCHEMBL24469637 | 0.72 | CYP3A4 (0.55) | — | |
| SCHEMBL29666985 | 0.72 | CYP3A4 (0.55) | — | |
| SCHEMBL21667337 | 0.72 | CYP3A4 (0.53) | — | |
| SCHEMBL21667332 | 0.71 | CYP3A4 (0.49) | — | |
| SCHEMBL24469529 | 0.69 | CYP3A4 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022111498-A1 | PYRIMIDINEDIONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 江苏恒瑞医药股份有限公司 | 2022-06-02 | — | — | WO | disclosed |