Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29713112 | 1.00 | PTGS2 (0.61) | PTGS2ALDH1A1LMNAMAPK1KDM4E | |
| SCHEMBL29713157 | 0.89 | SLC26A4 (0.52) | PTGS2LMNAL3MBTL1POLBHTT | |
| SCHEMBL24470883 | 0.89 | SLC26A4 (0.52) | PTGS2LMNAL3MBTL1POLBHTT | |
| SCHEMBL12019229 | 0.78 | FFAR1 (0.59) | ALDH1A1LMNAMAPK1KDM4EMAPT | |
| SCHEMBL12019248 | 0.78 | FFAR1 (0.51) | MAPTPOLBFFAR1 | |
| SCHEMBL31604936 | 0.77 | PTGS2 (0.63) | PTGS2ALDH1A1LMNAMAPK1KDM4E | |
| SCHEMBL26676604 | 0.76 | ALDH1A1 (0.68) | PTGS2ALDH1A1LMNAMAPK1KDM4E | |
| SCHEMBL28654740 | 0.75 | PTGS2 (0.85) | PTGS2ALDH1A1LMNAMAPK1KDM4E | |
| SCHEMBL26676599 | 0.74 | ALDH1A1 (0.65) | PTGS2ALDH1A1LMNAMAPK1KDM4E | |
| SCHEMBL26676551 | 0.74 | ALDH1A1 (0.65) | PTGS2ALDH1A1LMNAMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116761796-A | Aryl derivatives for the treatment of TRPM3 mediated disorders | 勒芬天主教大学 | 2023-09-15 | — | — | CN | disclosed |
| WO-2022112345-A1 | ARYL DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-06-02 | — | — | WO | disclosed |