Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.69 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31735947 | 1.00 | KEAP1 (0.69) | KEAP1NFE2L2ALDH1A1ALOX15 | |
| SCHEMBL29698419 | 0.89 | KEAP1 (0.67) | KEAP1NFE2L2 | |
| SCHEMBL19129654 | 0.89 | KEAP1 (0.55) | KEAP1NFE2L2 | |
| SCHEMBL26859860 | 0.86 | KEAP1 (0.53) | KEAP1NFE2L2 | |
| SCHEMBL29698498 | 0.83 | KEAP1 (0.66) | KEAP1NFE2L2 | |
| SCHEMBL29698435 | 0.83 | KEAP1 (0.66) | KEAP1NFE2L2 | |
| SCHEMBL24473698 | 0.83 | KEAP1 (0.54) | KEAP1NFE2L2 | |
| SCHEMBL24473695 | 0.82 | KEAP1 (0.48) | KEAP1NFE2L2 | |
| SCHEMBL19129847 | 0.82 | KEAP1 (0.54) | KEAP1NFE2L2 | |
| SCHEMBL25046238 | 0.82 | KEAP1 (0.78) | KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220168253-A1 | PRODUCTION PROMOTER OF TYPE I COLLAGEN OR ELASTIN | DR'S CHOICE CO., LTD. (JP) | 2022-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220168253-A1 | PRODUCTION PROMOTER OF TYPE I COLLAGEN OR ELASTIN | COL14A1, COL2A1, COL1A1 | KEAP1 746/4885NFE2L2 2052/4885ALDH1A1 2987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.