SCHEMBL2447376

SCHEMBL2447376

C=COc1ccc(C=Cc2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.51
ALDH1A1 P00352 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
FBP1 P09467 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
RARA P10276 2/20 0.45
RARB P10826 2/20 0.45
RARG P13631 2/20 0.45
APP P05067 1/20 0.43
ABL1 P00519 1/20 0.43
EGFR P00533 1/20 0.43
ABL2 P42684 1/20 0.43
KMT2A Q03164 2/20 0.43
TP53 P04637 1/20 0.43
TSHR P16473 1/20 0.43
PARP15 Q460N3 1/20 0.42
PARP10 Q53GL7 1/20 0.42
F3 P13726 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2447375 1.00 XDH (0.51) XDHALDH1A1L3MBTL1FBP1CA1
SCHEMBL2446002 0.91 CA1 (0.54) ALDH1A1L3MBTL1CA1CA2KMT2A
SCHEMBL2446927 0.85 HSD17B10 (0.55) ALDH1A1L3MBTL1CA1CA2RARB
SCHEMBL20032247 0.81 PARP10 (0.62) XDHALDH1A1L3MBTL1FBP1CA1
SCHEMBL2615887 0.80 ALDH1A1 (0.68) XDHALDH1A1L3MBTL1FBP1CA1
SCHEMBL69167 0.80 ALDH1A1 (0.68) XDHALDH1A1L3MBTL1FBP1CA1
SCHEMBL9681088 0.80 ALDH1A1 (0.68) XDHALDH1A1L3MBTL1FBP1CA1
SCHEMBL9339856 0.80 ALDH1A1 (0.68) XDHALDH1A1L3MBTL1FBP1CA1
SCHEMBL9681086 0.80 ALDH1A1 (0.68) XDHALDH1A1L3MBTL1FBP1CA1
SCHEMBL2126364 0.80 ALDH1A1 (0.68) XDHALDH1A1L3MBTL1FBP1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2006351-B1 LIQUID-CRYSTALLINE COMPOSITION WITH IMPROVED ADHESION, LIQUID-CRYSTAL FILM COMPRISING THE COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT EMPLOYING THE FILM NIPPON OIL CORP (JP) 2011-10-12 EP disclosed
EP-1422255-B1 MAIN CHAIN TYPE LIQUID CRYSTAL POLYESTER LIQUID CRYSTALLINE COMPOSITION METHOD FOR PRODUCING LIQUID CRYSTAL FILM OPTICAL FILM AND DISPLAY NIPPON OIL CORP (JP) 2011-09-28 EP disclosed
US-20100208182-A1 METHOD FOR MANUFACTURING OPTICAL FILM NIPPON OIL CORPORATION (JP) 2010-08-19 US disclosed
US-7763182-B2 Liquid crystalline composition with improved adhesivity, liquid crystal film comprising the composition, and liquid crystal display device equipped with the film NIPPON OIL CORPORATION (JP) 2010-07-27 US disclosed
EP-2202546-A1 METHOD FOR PRODUCING OPTICAL FILM Nippon Oil Corporation (JP) 2010-06-30 EP disclosed
US-20090208673-A1 Liquid Crystalline Composition with Improved Adhesivity, Liquid Crystal Film Comprising the Composition, and Liquid Crystal Display Device Equipped with the Film NIPPON OIL CORPORATION (JP) 2009-08-20 US disclosed
EP-2006351-A9 LIQUID-CRYSTALLINE COMPOSITION WITH IMPROVED ADHESION, LIQUID-CRYSTAL FILM COMPRISING THE COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT EMPLOYING THE FILM Nippon Oil Corporation (JP) 2009-07-01 EP disclosed
EP-2006351-A2 LIQUID-CRYSTALLINE COMPOSITION WITH IMPROVED ADHESION, LIQUID-CRYSTAL FILM COMPRISING THE COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT EMPLOYING THE FILM Nippon Oil Corporation (JP) 2008-12-24 EP disclosed
US-6894141-B2 Main chain type liquid crystalline polyester, liquid crystalline composition, method for producing liquid crystal film and optical film, and display having optical film NIPPON OIL CORPORATION (JP) 2005-05-17 US disclosed
US-20040171788-A1 Main chain type liquid crystal polyester, liquid crystalline composition, method for producing liquid crystal film, optical film and display NOBLE VENTURE FINANCE I LIMITED (GB) 2004-09-02 US disclosed
EP-1422255-A1 MAIN CHAIN TYPE LIQUID CRYSTAL POLYESTER LIQUID CRYSTALLINE COMPOSITION METHOD FOR PRODUCING LIQUID CRYSTAL FILM OPTICAL FILM AND DISPLAY Nippon Oil Corporation (JP) 2004-05-26 EP disclosed