Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 4/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1244071 | 0.84 | PPARG (0.52) | PPARDPPARGPPARAHTTLMNA | |
| SCHEMBL13484525 | 0.82 | PPARD (0.54) | PPARDPPARGPPARAHTTLMNA | |
| SCHEMBL5108537 | 0.81 | ALDH1A1 (0.57) | PPARDPPARGPPARAHTTLMNA | |
| SCHEMBL4186855 | 0.81 | PPARD (0.55) | PPARDPPARGPPARAHTTLMNA | |
| SCHEMBL28827968 | 0.81 | HPGD (0.62) | HTTLMNAKDM4EPOLBGAA | |
| SCHEMBL1777832 | 0.80 | PPARD (0.49) | PPARDPPARGPPARAHTTLMNA | |
| SCHEMBL4181337 | 0.80 | PPARD (0.49) | PPARDPPARGPPARAHTTLMNA | |
| SCHEMBL4181344 | 0.80 | PPARD (0.49) | PPARDPPARGPPARAHTTKDM4E | |
| SCHEMBL1245338 | 0.80 | LMNA (0.50) | HTTLMNAKDM4EPOLBTSHR | |
| SCHEMBL4887579 | 0.78 | CYP1A2 (0.69) | HTTLMNAKDM4EPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022115326-A1 | METHODS OF MAKING A PPAR-DELTA AGONIST | RENEO PHARMACEUTICALS, INC. (US) | 2022-06-02 | — | — | WO | disclosed |