SCHEMBL4887579

SCHEMBL4887579

COC(=O)COc1ccc(Cl)cc1C

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.69
CYP2C9 P11712 1/20 0.69
HIF1A Q16665 1/20 0.69
MEN1 O00255 1/20 0.62
KMT2A Q03164 1/20 0.62
MAPT P10636 2/20 0.61
ESR1 P03372 1/20 0.61
POLB P06746 1/20 0.61
ESR2 Q92731 1/20 0.61
CTDSP1 Q9GZU7 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
LMNA P02545 5/20 0.60
KDM4E B2RXH2 2/20 0.60
NPSR1 Q6W5P4 1/20 0.60
KCNH2 Q12809 1/20 0.60
SMN1; SMN2 Q16637 3/20 0.59
HPGD P15428 2/20 0.59
PTGDR Q13258 1/20 0.59
PTGDR2 Q9Y5Y4 1/20 0.59
NPC1 O15118 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27351928 0.87 CYP1A2 (0.69) CYP1A2CYP2C9HIF1AMEN1KMT2A
SCHEMBL1107026 0.87 LMNA (0.57) CYP1A2CYP2C9HIF1AMEN1KMT2A
SCHEMBL5416139 0.86 CYP1A2 (0.68) CYP1A2CYP2C9HIF1AMEN1KMT2A
2,4-Dichlorophenoxyacetic Acid, Methyl Ester SCHEMBL5004223 0.85 MAPT (0.70) CYP1A2MEN1KMT2AMAPTTDP1
SCHEMBL9487034 0.84 KDM4E (0.66) CYP1A2CYP2C9HIF1AMEN1KMT2A
SCHEMBL1107029 0.84 PTGDR (0.59) CYP1A2CYP2C9HIF1AMEN1KMT2A
SCHEMBL11640730 0.83 CYP1A2 (0.64) CYP1A2CYP2C9HIF1AMEN1KMT2A
SCHEMBL8605798 0.83 CYP1A2 (0.64) CYP1A2CYP2C9HIF1AMEN1KMT2A
SCHEMBL28827968 0.83 HPGD (0.62) MEN1KMT2AMAPTPOLBTDP1
SCHEMBL1195318 0.83 CYP1A2 (0.64) CYP1A2CYP2C9HIF1AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 265 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
CN-119306591-A Method for generating phenoxycarboxylic acid by utilizing acid exchange 山东润博生物科技有限公司 2025-01-14 CN claimed
EP-4337017-A1 HERBICIDE/SAFENER COMBINATION BASED ON SAFENERS FROM THE CLASS OF SUBSTITUTED [(1,5-DIPHENYL-1H-1,2,4-TRIAZOL-3-YL)OXY]ACETIC ACIDS AND THEIR SALTS Bayer Aktiengesellschaft (DE) 2024-03-20 EP claimed
US-20230000079-A1 COMBINATION COMPRISING A TRIKETONE HERBICIDE AND A DIPHENYLETHER HERBICIDE, AND A METHOD FOR MAKING AND USING THE COMBINATION Generic Crop Science LLC (US) 2023-01-05 US claimed
WO-2022152728-A1 HERBICIDAL COMPOSITIONS BAYER AKTIENGESELLSCHAFT (DE) 2022-07-21 WO claimed
US-20080242544-A1 Phytoactive Composition MICAP PLC (GB) 2008-10-02 US claimed
EP-1750504-A1 PHYTOACTIVE COMPOSITION MICAP PLC. (GB) 2007-02-14 EP claimed
WO-2005102045-A1 PHYTOACTIVE COMPOSITION MICAP PLC (GB) 2005-11-03 WO claimed
US-12604894-B2 Solid pesticidal formulation SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2026-04-21 US disclosed
US-12568967-B2 Compositions comprising pyridine carboxylate herbicides with synthetic auxin herbicides or auxin transport inhibitors CORTEVA AGRISCIENCE LLC (US) 2026-03-10 US disclosed
US-20260047579-A1 METHOD OF CONTROLLING WEEDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2026-02-19 US disclosed
US-20260042731-A1 (2,4-DICHLOROPHENOXY)ACETIC ACID ANALOGS CORTEVA AGRISCIENCE LLC (US) 2026-02-12 US disclosed
US-12543737-B2 Herbicidal composition and method for controlling weeds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2026-02-10 US disclosed
US-20260007133-A1 HERBICIDAL COMPOSITION COMPRISING AZINE COMPOUNDS BASF SE (DE) 2026-01-08 US disclosed
US-20140116112-A1 METHODS FOR DETERMINING THE PRESENCE OR ABSENCE OF CONTAMINANTS IN A SAMPLE K & D LABORATORIES, INC. (US) 2014-05-01 US disclosed
US-20080242544-A1 Phytoactive Composition MICAP PLC (GB) 2008-10-02 US disclosed
US-20070135307-A1 Inhibition of tuber sprouting ACETO AGRICULTURAL CHEMICALS CORP. (US) 2007-06-14 US disclosed
WO-2007044200-A2 INHIBITION OF TUBER SPROUTING ACETO AGRICULTURAL CHEMICALS CORPORATION (US) 2007-04-19 WO disclosed
EP-1750504-A1 PHYTOACTIVE COMPOSITION MICAP PLC. (GB) 2007-02-14 EP disclosed
WO-2005102045-A1 PHYTOACTIVE COMPOSITION MICAP PLC (GB) 2005-11-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135307-A1 Inhibition of tuber sprouting PF4, PDGFA, PDGFRB CYP1A2 2130/4885CYP2C9 2225/4885HIF1A 1213/4885
US-20230000079-A1 COMBINATION COMPRISING A TRIKETONE HERBICIDE AND A DIPHENYLETHER HERBICIDE, AND A METHOD FOR MAKING AND USING THE COMBINATION DDT, TDO2, DNTT CYP1A2 430/4885CYP2C9 3351/4885HIF1A 1841/4885
US-12568967-B2 Compositions comprising pyridine carboxylate herbicides with synthetic auxin herbicides or auxin transport inhibitors DDT, SLC16A3, HPD CYP1A2 123/4885CYP2C9 223/4885HIF1A 3539/4885
US-20080242544-A1 Phytoactive Composition PNMT, ACHE, TACR1 CYP1A2 113/4885CYP2C9 1707/4885HIF1A 2280/4885
US-12543737-B2 Herbicidal composition and method for controlling weeds PRDX6, PPOX, PRDX2 CYP1A2 1837/4885CYP2C9 863/4885HIF1A 4618/4885
US-20260007133-A1 HERBICIDAL COMPOSITION COMPRISING AZINE COMPOUNDS CBR3, CBR1, DDT CYP1A2 30/4885CYP2C9 240/4885HIF1A 3842/4885
US-20260047579-A1 METHOD OF CONTROLLING WEEDS WIZ, CYP4X1, CYP2C18 CYP1A2 13/4885CYP2C9 30/4885HIF1A 4580/4885
US-20260042731-A1 (2,4-DICHLOROPHENOXY)ACETIC ACID ANALOGS DDT, AADAC, HACL2 CYP1A2 515/4885CYP2C9 601/4885HIF1A 4386/4885
US-12604894-B2 Solid pesticidal formulation DDT, TPP1, CHI3L2 CYP1A2 1526/4885CYP2C9 769/4885HIF1A 4881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.