Ethisterone

Ethisterone

SCHEMBL24475

C#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 8/20 1.00
SHBG P04278 7/20 1.00
SMN1; SMN2 Q16637 5/20 1.00
TSHR P16473 5/20 1.00
NR3C1 P04150 4/20 1.00
CYP2C19 P33261 4/20 1.00
PGR P06401 3/20 1.00
HIF1A Q16665 3/20 1.00
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
ESR1 P03372 2/20 1.00
THRB P10828 1/20 1.00
AR P10275 1/20 1.00
ALDH1A1 P00352 4/20 0.72
ADRA1A P35348 1/20 0.72
HTR2B P41595 1/20 0.72
BLM P54132 5/20 0.67
SERPINA6 P08185 4/20 0.67
MAPT P10636 3/20 0.67
ADORA3 P0DMS8 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethisterone SCHEMBL7604035 1.00 LMNA (1.00) LMNASHBGSMN1; SMN2TSHRNR3C1
Ethisterone SCHEMBL606819 1.00 LMNA (1.00) LMNASHBGSMN1; SMN2TSHRNR3C1
Ethisterone SCHEMBL15581276 1.00 LMNA (1.00) LMNASHBGSMN1; SMN2TSHRNR3C1
Ethisterone SCHEMBL14433089 1.00 LMNA (1.00) LMNASHBGSMN1; SMN2TSHRNR3C1
Ethisterone SCHEMBL12417537 1.00 LMNA (1.00) LMNASHBGSMN1; SMN2TSHRNR3C1
Ethisterone SCHEMBL16864523 1.00 LMNA (1.00) LMNASHBGSMN1; SMN2TSHRNR3C1
Ethisterone SCHEMBL16691330 1.00 LMNA (1.00) LMNASHBGSMN1; SMN2TSHRNR3C1
Ethisterone SCHEMBL780055 1.00 LMNA (1.00) LMNASHBGSMN1; SMN2TSHRNR3C1
Ethisterone SCHEMBL28541256 0.99 LMNA (0.98) LMNASHBGSMN1; SMN2TSHRNR3C1
Ethisterone SCHEMBL11152514 0.96 LMNA (0.92) LMNASHBGSMN1; SMN2TSHRNR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4342 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250195450-A1 BIOERODIBLE DRUG DELIVERY IMPLANTS HERA HEALTH SOLUTIONS INC. 2025-06-19 US claimed
US-12318395-B2 Ethinyl estradiol-β-cyclodextrin complex and process for preparing thereof LABORATORIOS LEON FARMA, S.A. (ES) 2025-06-03 US claimed
EP-3884914-B1 AN OVERMOULDABLE SUBSTRATE AND USES THEREOF QPHARMA AB (SE) 2025-05-21 EP claimed
US-20250152556-A1 ETRASIMOD FOR USE IN TREATING S1P1 RECEPTOR-ASSOCIATED DISORDERS IN COMBINATION WITH HORMONE TREATMENT ARENA PHARMACEUTICALS, INC. (US) 2025-05-15 US claimed
WO-2025044131-A1 METHODS FOR PRODUCING OPHTHALMIC COMPOSITION OF POORLY WATER-SOLUBLE DRUGS THERATOCULAR BIOTEK CO., LTD. (CN) 2025-03-06 WO claimed
US-12178824-B2 Orodispersible formulations MILLICENT PHARMA LIMITED (IE) 2024-12-31 US claimed
CN-119125584-A Testosterone immunoassay reagent sample release agent formula 深圳市辰纳生物科技有限公司 2024-12-13 CN claimed
CN-119097706-A Natural product for preventing and treating vascular calcification and application thereof 江南大学 2024-12-10 CN claimed
CN-118541151-A Is Qu Mode for use in combination with hormonal therapy for the treatment of S1P1 receptor related disorders 艾尼纳制药公司 2024-08-23 CN claimed
CN-117877666-A XGBoost algorithm-based method for guiding gonadotrophin initial administration dosage selection 云南大学 2024-04-12 CN claimed
US-4622244-A SOLIDIFICATION THE WASHINGTON UNIVERSITY (US) 1986-11-11 US claimed
US-4540564-A DIHYDROPYRIDINE AND/OR PYRIDINIUM SALT REDOX CARRIER UNIVERSITY OF FLORIDA (US) 1985-09-10 US claimed
EP-0110955-A1 BRAIN-SPECIFIC DRUG DELIVERY. UNIV FLORIDA (US) 1984-06-20 EP claimed
WO-1983003968-A1 BRAIN-SPECIFIC DRUG DELIVERY UNIVERSITY OF FLORIDA (US) 1983-11-24 WO claimed
US-4346709-A Drug delivery devices comprising erodible polymer and erosion rate modifier ALZA CORPORATION (US) 1982-08-31 US claimed
EP-0050867-A1 Vaginal ring SCHERING AKTIENGESELLSCHAFT (DE) 1982-05-05 EP claimed
US-4211701-A Spironolactone process THE UPJOHN COMPANY (US) 1980-07-08 US claimed
US-4057542-A Process for the preparation of 17β-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactone G. D. SEARLE & CO. (US) 1977-11-08 US claimed
US-4016270-A Method for treating dysmenorrhea with a uterine therapeutic system ALZA CORPORATION (US) 1977-04-05 US claimed
US-4014988-A Method for treating hypermenorrhea with uterine therapeutic system ALZA CORPORATION (US) 1977-03-29 US claimed