Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 1.00 |
| ▸ | SHBG | P04278 | 7/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 1.00 |
| ▸ | TSHR | P16473 | 5/20 | 1.00 |
| ▸ | NR3C1 | P04150 | 4/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 4/20 | 1.00 |
| ▸ | PGR | P06401 | 3/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | ESR1 | P03372 | 2/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 1.00 |
| ▸ | AR | P10275 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.72 |
| ▸ | HTR2B | P41595 | 1/20 | 0.72 |
| ▸ | BLM | P54132 | 5/20 | 0.67 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethisterone SCHEMBL7604035 | 1.00 | LMNA (1.00) | LMNASHBGSMN1; SMN2TSHRNR3C1 | |
| Ethisterone SCHEMBL606819 | 1.00 | LMNA (1.00) | LMNASHBGSMN1; SMN2TSHRNR3C1 | |
| Ethisterone SCHEMBL15581276 | 1.00 | LMNA (1.00) | LMNASHBGSMN1; SMN2TSHRNR3C1 | |
| Ethisterone SCHEMBL14433089 | 1.00 | LMNA (1.00) | LMNASHBGSMN1; SMN2TSHRNR3C1 | |
| Ethisterone SCHEMBL24475 | 1.00 | LMNA (1.00) | LMNASHBGSMN1; SMN2TSHRNR3C1 | |
| Ethisterone SCHEMBL16864523 | 1.00 | LMNA (1.00) | LMNASHBGSMN1; SMN2TSHRNR3C1 | |
| Ethisterone SCHEMBL16691330 | 1.00 | LMNA (1.00) | LMNASHBGSMN1; SMN2TSHRNR3C1 | |
| Ethisterone SCHEMBL780055 | 1.00 | LMNA (1.00) | LMNASHBGSMN1; SMN2TSHRNR3C1 | |
| Ethisterone SCHEMBL28541256 | 0.99 | LMNA (0.98) | LMNASHBGSMN1; SMN2TSHRNR3C1 | |
| Ethisterone SCHEMBL11152514 | 0.96 | LMNA (0.92) | LMNASHBGSMN1; SMN2TSHRNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11766480-B2 | Multivalent peptoid oligomers, pharmaceutical compositions and methods of using same | NEW YORK UNIVERSITY (US) | 2023-09-26 | — | — | US | disclosed |
| US-11766480-B2 | Multivalent peptoid oligomers, pharmaceutical compositions and methods of using same | NEW YORK UNIVERSITY (US) | 2023-09-26 | — | — | US | disclosed |
| US-8722651-B2 | Methods and products for treatment of diseases | AMPIO PHARMACEUTICALS, INC. (US) | 2014-05-13 | — | — | US | disclosed |
| US-8722651-B2 | Methods and products for treatment of diseases | AMPIO PHARMACEUTICALS, INC. (US) | 2014-05-13 | — | — | US | disclosed |
| EP-1919290-B1 | METHODS AND PRODUCTS FOR TREATMENT OF DISEASES | AMPIO PHARMACEUTICALS INC (US) | 2014-01-22 | — | — | EP | disclosed |
| US-8586568-B2 | Methods and products for treatment of diseases | AMPIO PHARMACEUTICALS, INC. (US) | 2013-11-19 | — | — | US | disclosed |
| US-8586568-B2 | Methods and products for treatment of diseases | AMPIO PHARMACEUTICALS, INC. (US) | 2013-11-19 | — | — | US | disclosed |
| US-20110171307-A1 | METHODS AND PRODUCTS FOR TREATMENT OF DISEASES | AMPIO PHARMACEUTICALS, INC. | 2011-07-14 | — | — | US | disclosed |
| US-20110171306-A1 | METHODS AND PRODUCTS FOR TREATMENT OF DISEASES | AMPIO PHARMACEUTICALS, INC. | 2011-07-14 | — | — | US | disclosed |
| US-7495107-B2 | Method for manufacturing isoxazole derivative or dihydroisoxazole derivative | RIKKYO GAKUIN (JP) | 2009-02-24 | — | — | US | disclosed |
| US-7495107-B2 | Method for manufacturing isoxazole derivative or dihydroisoxazole derivative | RIKKYO GAKUIN (JP) | 2009-02-24 | — | — | US | disclosed |
| US-20070111972-A1 | \"METHODS AND PRODUCTS FOR TREATMENT OF DISEASES\ | DMI BIOSCIENCES, INC. (US) | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110171306-A1 | METHODS AND PRODUCTS FOR TREATMENT OF DISEASES | VEGFA, PGF, BDNF | LMNA 3384/4885SHBG 191/4885SMN1; SMN2 150/4885 |
| US-20070111972-A1 | \"METHODS AND PRODUCTS FOR TREATMENT OF DISEASES\ | PGF, VEGFA, BDNF | LMNA 3120/4885SHBG 118/4885SMN1; SMN2 91/4885 |
| US-11766480-B2 | Multivalent peptoid oligomers, pharmaceutical compositions and methods of using same | AR, SHBG, KLK3 | LMNA 3909/4885SHBG 2/4885SMN1; SMN2 3094/4885 |
| US-20110171307-A1 | METHODS AND PRODUCTS FOR TREATMENT OF DISEASES | VEGFA, PGF, BDNF | LMNA 3384/4885SHBG 191/4885SMN1; SMN2 150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.