SCHEMBL24475772

SCHEMBL24475772

c1ccc(-c2ccc3ccc(-c4ccc5ccc(-c6ccccn6)nc5c4)cc3n2)nc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.55
LMNA P02545 5/20 0.55
SMN1; SMN2 Q16637 4/20 0.55
TP53 P04637 4/20 0.55
CCR1 P32246 3/20 0.55
CCR5 P51681 3/20 0.55
CCR8 P51685 3/20 0.55
ALOX15 P16050 2/20 0.55
HTT P42858 2/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
ALPL P05186 1/20 0.55
HSP90AA1 P07900 1/20 0.55
ALPI P09923 1/20 0.55
ALPG P10696 1/20 0.55
MAPK1 P28482 1/20 0.55
CYP1A2 P05177 2/20 0.52
POLB P06746 2/20 0.52
METAP1 P53582 2/20 0.52
BLM P54132 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22281912 0.93 KDM4E (0.48) KDM4ELMNASMN1; SMN2TP53CCR1
SCHEMBL24475498 0.93 NPC1 (0.49) KDM4ELMNASMN1; SMN2TP53CCR1
SCHEMBL24454171 0.93 KDM4E (0.52) KDM4ELMNASMN1; SMN2TP53CCR1
SCHEMBL24454278 0.92 KDM4E (0.47) KDM4ELMNASMN1; SMN2TP53CCR1
SCHEMBL20208052 0.91 KDM4E (0.46) KDM4ELMNASMN1; SMN2TP53CCR1
SCHEMBL22970258 0.91 KDM4E (0.50) KDM4ELMNASMN1; SMN2TP53CCR1
SCHEMBL24475589 0.91 KDM4E (0.50) KDM4ELMNASMN1; SMN2TP53CCR1
SCHEMBL24475836 0.89 KDM4E (0.44) KDM4ELMNASMN1; SMN2TP53CCR1
SCHEMBL24475457 0.88 RAB9A (0.46) KDM4ELMNASMN1; SMN2TP53CCR1
SCHEMBL22282134 0.88 TOP1 (0.43) KDM4ELMNASMN1; SMN2TP53CCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220173329-A1 COMPOUND, ORGANIC OPTOELECTRONIC DIODE, AND DISPLAY DEVICE LT MATERIALS CO., LTD. (KR) 2022-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220173329-A1 COMPOUND, ORGANIC OPTOELECTRONIC DIODE, AND DISPLAY DEVICE OXER1, OCIAD1, OR10J3 KDM4E 3814/4885LMNA 4856/4885SMN1; SMN2 4030/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.