SCHEMBL20208052

SCHEMBL20208052

Brc1ccc(-c2ccc3ccc(-c4ccccn4)nc3c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.46
LMNA P02545 7/20 0.46
TP53 P04637 4/20 0.46
SMN1; SMN2 Q16637 4/20 0.46
HTT P42858 3/20 0.46
CCR1 P32246 3/20 0.46
CCR5 P51681 3/20 0.46
CCR8 P51685 3/20 0.46
ALOX15 P16050 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
ALPL P05186 1/20 0.46
HSP90AA1 P07900 1/20 0.46
ALPI P09923 1/20 0.46
ALPG P10696 1/20 0.46
MAPK1 P28482 1/20 0.46
CYP1A2 P05177 2/20 0.44
CYP2C19 P33261 1/20 0.44
POLB P06746 1/20 0.42
METAP1 P53582 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21308795 0.91 CYP11B1 (0.47) KDM4ELMNATP53SMN1; SMN2HTT
SCHEMBL24475772 0.91 KDM4E (0.55) KDM4ELMNATP53SMN1; SMN2HTT
SCHEMBL29758372 0.87 HTT (0.58) KDM4ELMNATP53SMN1; SMN2HTT
SCHEMBL22970594 0.87 HTT (0.58) KDM4ELMNATP53SMN1; SMN2HTT
SCHEMBL24454278 0.86 KDM4E (0.47) KDM4ELMNATP53SMN1; SMN2HTT
SCHEMBL22281912 0.84 KDM4E (0.48) KDM4ELMNATP53SMN1; SMN2HTT
SCHEMBL24475498 0.84 NPC1 (0.49) KDM4ELMNATP53SMN1; SMN2HTT
SCHEMBL24454171 0.84 KDM4E (0.52) KDM4ELMNATP53SMN1; SMN2HTT
SCHEMBL24475836 0.84 KDM4E (0.44) KDM4ELMNATP53SMN1; SMN2HTT
SCHEMBL20208228 0.83 KDM4E (0.43) KDM4ELMNATP53SMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11248008-B2 Heterocyclic compound and organic light emitting element using same LT MATERIALS CO., LTD. (KR) 2022-02-15 US disclosed
US-20190263834-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING SAME HEESUNG MATERIAL LTD. (KR) 2019-08-29 US disclosed
WO-2018097648-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING SAME 희성소재(주) 2018-05-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190263834-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING SAME CRY1, CRY2, CYP1A1 KDM4E 3716/4885LMNA 3579/4885TP53 4479/4885
US-11248008-B2 Heterocyclic compound and organic light emitting element using same CRY1, CRY2, CYP1A1 KDM4E 3716/4885LMNA 3579/4885TP53 4479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.