Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18462938 | 0.79 | ALDH1A1 (0.36) | ECE1ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL17305531 | 0.79 | ALDH1A1 (0.55) | CTSSCTSKECE1ALDH1A1LMNA | |
| SCHEMBL22695761 | 0.79 | ALDH1A1 (0.36) | CTSSCTSKECE1ALDH1A1LMNA | |
| SCHEMBL23743699 | 0.79 | ALDH1A1 (0.36) | CTSSCTSKECE1ALDH1A1LMNA | |
| SCHEMBL3338670 | 0.79 | ALDH1A1 (0.55) | CTSSCTSKECE1ALDH1A1LMNA | |
| SCHEMBL19295807 | 0.79 | ALDH1A1 (0.36) | ECE1ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL29697722 | 0.79 | ALDH1A1 (0.55) | CTSSCTSKECE1ALDH1A1LMNA | |
| SCHEMBL14410302 | 0.78 | ALDH1A1 (0.39) | ECE1ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL20756387 | 0.77 | ALDH1A1 (0.35) | CTSSCTSKECE1ALDH1A1LMNA | |
| SCHEMBL22814739 | 0.77 | ALDH1A1 (0.35) | CTSSCTSKECE1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022115477-A1 | BCL-XL INHIBITOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF | NOVARTIS AG (CH) | 2022-06-02 | — | — | WO | disclosed |