Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ECE1 | P42892 | 2/20 | 0.53 |
| ▸ | MME | P08473 | 4/20 | 0.47 |
| ▸ | ACE | P12821 | 3/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.35 |
| ▸ | CTH | P32929 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29697722 | 1.00 | ALDH1A1 (0.55) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL17305531 | 1.00 | ALDH1A1 (0.55) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL23743699 | 0.83 | ALDH1A1 (0.36) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL22695761 | 0.83 | ALDH1A1 (0.36) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL20756387 | 0.82 | ALDH1A1 (0.35) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL22814739 | 0.82 | ALDH1A1 (0.35) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL25672015 | 0.82 | ALDH1A1 (0.35) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL26077042 | 0.82 | ALDH1A1 (0.35) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL21261769 | 0.80 | LMNA (0.52) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL30493820 | 0.80 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPTPTGS2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109796519-B | Steroid compound and application thereof | 河北科技大学 | 2023-01-10 | — | — | CN | disclosed |
| US-20100152156-A1 | 2-Azetidinone Derivatives For The Treatment Of Hyperlipidaemic Diseases | ASTRAZENECA AB (SE) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152156-A1 | 2-Azetidinone Derivatives For The Treatment Of Hyperlipidaemic Diseases | NPC1L1, CYP46A1, PCSK9 | ALDH1A1 747/4885LMNA 1434/4885MAPT 3880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.