Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PDE6D | O43924 | 1/20 | 0.34 |
| ▸ | PDE8A | O60658 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | PDE9A | O76083 | 1/20 | 0.34 |
| ▸ | PDE8B | O95263 | 1/20 | 0.34 |
| ▸ | PDE6A | P16499 | 1/20 | 0.34 |
| ▸ | PDE6G | P18545 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE6B | P35913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24477338 | 0.76 | KDM4E (0.46) | ALDH1A1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29033147 | 0.70 | ALDH1A1 (0.40) | ALDH1A1POLBMEN1KMT2ARXFP1 | |
| SCHEMBL20893066 | 0.70 | RXFP1 (0.40) | ALDH1A1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13424035 | 0.70 | ALDH1A1 (0.37) | ALDH1A1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24477504 | 0.69 | PDE2A (0.38) | ALDH1A1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9264821 | 0.68 | ALDH1A1 (0.52) | ALDH1A1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24477519 | 0.67 | MEN1 (0.37) | ALDH1A1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24477316 | 0.67 | MEN1 (0.46) | ALDH1A1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24477383 | 0.67 | MEN1 (0.44) | ALDH1A1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24477317 | 0.67 | MEN1 (0.46) | ALDH1A1POLBMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022111473-A1 | COMPOUNDS AS MRGPRX2 ANTAGONISTS | BIOARDIS LLC (US) | 2022-06-02 | — | — | WO | disclosed |