SCHEMBL29033147

SCHEMBL29033147

Nc1cn2c(n1)[nH]c1ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
RXFP1 Q9HBX9 2/20 0.40
PARP1 P09874 2/20 0.40
CA5A P35218 1/20 0.39
POLB P06746 1/20 0.38
AOC3 Q16853 3/20 0.36
MASP2 O00187 1/20 0.36
MEN1 O00255 1/20 0.36
NUDT1 P36639 1/20 0.36
KMT2A Q03164 1/20 0.36
DAO P14920 1/20 0.34
PSMB8 P28062 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
AURKA O14965 1/20 0.34
MAP4K4 O95819 1/20 0.34
TAOK1 Q7L7X3 1/20 0.34
PBK Q96KB5 1/20 0.34
SLK Q9H2G2 1/20 0.34
KDM4E B2RXH2 1/20 0.34
PLAUR Q03405 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20893066 0.79 RXFP1 (0.40) ALDH1A1RXFP1PARP1POLBMEN1
SCHEMBL9264821 0.76 ALDH1A1 (0.52) ALDH1A1RXFP1PARP1POLBMEN1
SCHEMBL13424035 0.75 ALDH1A1 (0.37) ALDH1A1RXFP1PARP1POLBMEN1
SCHEMBL8510 0.73 PARP1 (0.42) ALDH1A1RXFP1PARP1POLBMEN1
SCHEMBL9265898 0.71 KDM4E (0.55) ALDH1A1PARP1MEN1KMT2AKDM4E
SCHEMBL24477339 0.70 ALDH1A1 (0.36) ALDH1A1RXFP1PARP1POLBMEN1
SCHEMBL5351084 0.70 PARP1 (0.50) ALDH1A1RXFP1PARP1POLBMEN1
SCHEMBL21415948 0.67 KDM4E (0.42) ALDH1A1RXFP1POLBMEN1KMT2A
SCHEMBL1698065 0.67 KDM4E (0.53) ALDH1A1MEN1KMT2ANPSR1AURKA
SCHEMBL3212919 0.67 ALDH1A1 (0.46) ALDH1A1RXFP1PARP1POLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116381087-A Method for simultaneously detecting 17 kinds of hot processing hazardous substances in class 4 and application thereof 中国农业大学 2023-07-04 CN claimed
CN-116381087-A Method for simultaneously detecting 17 kinds of hot processing hazardous substances in class 4 and application thereof 中国农业大学 2023-07-04 CN disclosed