Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 4/20 | 0.46 |
| ▸ | MTOR | P42345 | 2/20 | 0.46 |
| ▸ | PRKDC | P78527 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | CCND2 | P30279 | 1/20 | 0.40 |
| ▸ | CCND3 | P30281 | 1/20 | 0.40 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24478472 | 0.90 | PIK3CA (0.43) | PIK3CAMTORPRKDCKDM4EMAPT | |
| SCHEMBL27101015 | 0.90 | NPBWR1 (0.43) | PIK3CAMTORPRKDCKDM4EMAPT | |
| SCHEMBL26879396 | 0.85 | OPRM1 (0.42) | PIK3CAMTORPRKDCKDM4EMAPT | |
| SCHEMBL27100950 | 0.84 | PIK3CA (0.47) | PIK3CAMTORPRKDCOPRM1OPRD1 | |
| SCHEMBL29712748 | 0.84 | PIK3CA (0.47) | PIK3CAMTORPRKDCOPRM1OPRD1 | |
| SCHEMBL27101052 | 0.84 | PIK3CA (0.48) | PIK3CAMTORPRKDCKDM4EMAPT | |
| SCHEMBL30586010 | 0.84 | PIK3CA (0.48) | PIK3CAMTORPRKDCKDM4EMAPT | |
| SCHEMBL24478444 | 0.83 | GPR119 (0.44) | PIK3CAMTORPRKDCKDM4EMAPT | |
| SCHEMBL24478649 | 0.82 | TP53 (0.46) | PIK3CAMTORPRKDCOPRM1OPRD1 | |
| SCHEMBL26676845 | 0.81 | GPR119 (0.46) | PIK3CAMTORPRKDCOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023229378-A1 | HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF | 주식회사 엘지화학 | 2023-11-30 | — | — | WO | disclosed |
| WO-2022114812-A1 | HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF | 주식회사 엘지화학 | 2022-06-02 | — | — | WO | disclosed |