SCHEMBL24478962

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15882584	0.76	AURKA (0.50)	DYRK1AAURKAJAK2MAP4K4FGFR1
	SCHEMBL13138395	0.74	DYRK1A (0.43)	DYRK1AAURKAJAK2MAP4K4FGFR1
	SCHEMBL859210	0.74	PRKD3 (0.49)	DYRK1AAURKAJAK2MAP4K4FGFR1
	SCHEMBL27678709	0.73	DYRK1A (0.44)	DYRK1AAURKAJAK2MAP4K4FGFR1
	SCHEMBL15882593	0.73	PLK4 (0.50)	DYRK1AAURKAJAK2MAP4K4FGFR1
	SCHEMBL19839227	0.73	GUSB (0.50)	CSNK2A1IDO1
	SCHEMBL24479128	0.72	PLK4 (0.37)	DYRK1AAURKAJAK2MAP4K4FGFR1
	SCHEMBL30768447	0.71	GUSB (0.55)	DYRK1AAURKAJAK2MAP4K4FGFR1
	SCHEMBL26696374	0.71	GUSB (0.55)	DYRK1AAURKAJAK2MAP4K4FGFR1
	SCHEMBL27775351	0.71	DYRK1A (0.43)	DYRK1AAURKAJAK2MAP4K4FGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.