Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25856190 | 0.89 | ACHE (0.42) | ACHE | |
| SCHEMBL24480556 | 0.83 | ACHE (0.35) | ACHE | |
| SCHEMBL25027097 | 0.83 | ACHE (0.39) | ACHE | |
| SCHEMBL25026638 | 0.83 | — | — | |
| SCHEMBL24185414 | 0.82 | HRH3 (0.32) | — | |
| SCHEMBL24480648 | 0.80 | POLB (0.33) | — | |
| SCHEMBL25924832 | 0.79 | KDM4E (0.36) | ACHE | |
| SCHEMBL25508404 | 0.78 | HRH3 (0.33) | — | |
| SCHEMBL22703779 | 0.78 | ACHE (0.61) | ACHE | |
| SCHEMBL24480377 | 0.77 | ACHE (0.41) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022111526-A1 | BENZENE RING DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 四川海思科制药有限公司 | 2022-06-02 | — | — | WO | disclosed |