Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24480221 | 0.89 | ACHE (0.39) | ACHE | |
| SCHEMBL24480376 | 0.85 | ACHE (0.42) | ACHENCF1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL24480864 | 0.84 | NCF1 (0.32) | NCF1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL25621909 | 0.84 | OPRL1 (0.34) | CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL24480648 | 0.83 | POLB (0.33) | — | |
| SCHEMBL25027097 | 0.83 | ACHE (0.39) | ACHE | |
| SCHEMBL25622107 | 0.83 | CACNA2D1 (0.36) | CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL25856204 | 0.82 | HRH3 (0.39) | NCF1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL25856385 | 0.82 | — | — | |
| SCHEMBL25508404 | 0.81 | HRH3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131167-A1 | COMPOUND FOR INHIBITING AND DEGRADING IRAK4, AND PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 海思科医药集团股份有限公司 | 2023-07-13 | — | — | WO | disclosed |