Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.31 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24480648 | 0.80 | POLB (0.33) | KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL24481348 | 0.79 | TSHR (0.33) | KDM4ETSHRGAA | |
| SCHEMBL15100017 | 0.79 | TSHR (0.40) | KDM4ETSHRGAASMN1; SMN2 | |
| SCHEMBL25508404 | 0.79 | HRH3 (0.33) | KDM4EPOLB | |
| SCHEMBL24480221 | 0.79 | ACHE (0.39) | ACHE | |
| SCHEMBL25027097 | 0.79 | ACHE (0.39) | ACHE | |
| SCHEMBL25856190 | 0.79 | ACHE (0.42) | ACHE | |
| SCHEMBL26743245 | 0.78 | — | — | |
| SCHEMBL18072438 | 0.77 | TSHR (0.39) | KDM4ETSHRGAACARM1PRMT6 | |
| SCHEMBL11919193 | 0.77 | KDM4E (0.50) | KDM4EPOLBKMT2ACARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109892-A1 | COMPOUND FOR INHIBITING OR DEGRADING BRD9, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 海思科医药集团股份有限公司 | 2023-06-22 | — | — | WO | disclosed |