SCHEMBL24480239

SCHEMBL24480239

CN1CCN(CC2CCN(CC3CN(C)C3)CC2)CC1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.44
NCF1 P14598 1/20 0.40
CHRM5 P08912 1/20 0.40
ADRA2C P18825 1/20 0.40
CACNA2D1 P54289 1/20 0.39
CACNA1B Q00975 1/20 0.39
CACNB1 Q02641 1/20 0.39
CACNA1C Q13936 1/20 0.39
SIGMAR1 Q99720 1/20 0.34
KCNH2 Q12809 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25571696 0.94 NCF1 (0.46) ACHENCF1CHRM5ADRA2CCACNA2D1
SCHEMBL22047347 0.91 ACHE (0.36) ACHENCF1CHRM5ADRA2CCACNA2D1
SCHEMBL24319476 0.89 NCF1 (0.50) ACHENCF1CHRM5ADRA2CCACNA2D1
SCHEMBL26705215 0.88 NCF1 (0.45) ACHENCF1CHRM5ADRA2CCACNA2D1
SCHEMBL23172474 0.87 NCF1 (0.48) ACHENCF1CHRM5ADRA2CCACNA2D1
SCHEMBL23172479 0.87 NCF1 (0.48) ACHENCF1CHRM5ADRA2CCACNA2D1
SCHEMBL25571704 0.87 NCF1 (0.48) ACHENCF1CHRM5ADRA2CCACNA2D1
SCHEMBL10202211 0.87 NCF1 (0.48) ACHENCF1CHRM5ADRA2CCACNA2D1
SCHEMBL26705153 0.87 NCF1 (0.43) ACHENCF1CHRM5ADRA2CCACNA2D1
SCHEMBL3436997 0.87 NCF1 (0.52) ACHENCF1CHRM5ADRA2CCACNA2D1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348427-A1 COMPOUND FOR ANDROGEN RECEPTOR DEGRADATION, AND PHARMACEUTICAL USE THEREOF UBIX THERAPEUTICS, INC. (KR) 2023-11-02 US disclosed
WO-2022111526-A1 BENZENE RING DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF 四川海思科制药有限公司 2022-06-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348427-A1 COMPOUND FOR ANDROGEN RECEPTOR DEGRADATION, AND PHARMACEUTICAL USE THEREOF AR, NR5A1, SHBG ACHE 3611/4885NCF1 3023/4885CHRM5 2288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.