Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 5/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.48 |
| ▸ | CHUK | O15111 | 1/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | AKT2 | P31751 | 1/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
| ▸ | BLK | P51451 | 1/20 | 0.46 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28319408 | 1.00 | PTPN11 (0.55) | PTPN11PTPN1PTPN6SMPD1CHUK | |
| SCHEMBL13957128 | 1.00 | PTPN11 (0.55) | PTPN11PTPN1PTPN6SMPD1CHUK | |
| SCHEMBL1776071 | 1.00 | PTPN11 (0.55) | PTPN11PTPN1PTPN6SMPD1CHUK | |
| SCHEMBL8974024 | 0.91 | PTPN11 (0.57) | PTPN11PTPN1PTPN6FPR2 | |
| SCHEMBL8975125 | 0.91 | THRA (0.53) | PTPN11PTPN1PTPN6SMPD1FPR2 | |
| SCHEMBL8974027 | 0.91 | SMPD1 (0.58) | PTPN11PTPN1PTPN6SMPD1FPR2 | |
| SCHEMBL12439893 | 0.90 | PTPN11 (0.48) | PTPN11PTPN1PTPN6SMPD1CHUK | |
| SCHEMBL7620596 | 0.88 | PTPN11 (0.49) | PTPN11PTPN1PTPN6SMPD1ALDH1A1 | |
| SCHEMBL2448597 | 0.86 | KDM4E (0.49) | PTPN11PTPN1PTPN6ALDH1A1HPGD | |
| SCHEMBL14506790 | 0.86 | PTPN11 (0.45) | PTPN11PTPN1PTPN6SMPD1CHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016193748-A1 | COMPOSITION | THE UNIVERSITY OF BIRMINGHAM (GB) | 2016-12-08 | — | — | WO | disclosed |
| US-7758932-B2 | Liquid crystal display device and display apparatus | RICOH COMPANY, LTD. (JP) | 2010-07-20 | — | — | US | disclosed |
| US-20080305280-A1 | LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY APPARATUS | RICOH COMPANY, LTD. | 2008-12-11 | — | — | US | disclosed |
| US-6689290-B2 | Family of conducting liquid crystals | THE UNIVERSITY OF LEEDS (GB) | 2004-02-10 | — | — | US | disclosed |
| US-20030160212-A1 | New family of conducting liquid crystals | UNIVERSITY OF LEEDS, THE (GB) | 2003-08-28 | — | — | US | disclosed |
| EP-1240272-A2 | A NEW FAMILY OF CONDUCTING LIQUID CRYSTALS | THE UNIVERSITY OF LEEDS (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001042391-A2 | A NEW FAMILY OF CONDUCTING LIQUID CRYSTALS | UNIVERSITY OF LEEDS (GB) | 2001-06-14 | — | — | WO | disclosed |
| EP-0703885-A1 | SYNTHESIS OF SUBSTITUTED TRIPHENYLENES, USEFUL AS DISCOTIC LIQUID CRYSTALS | BRITISH TECHNOLOGY GROUP LTD (GB) | 1996-04-03 | — | — | EP | disclosed |
| WO-1994029243-A1 | SYNTHESIS OF SUBSTITUTED TRIPHENYLENES, USEFUL AS DISCOTIC LIQUID CRYSTALS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1994-12-22 | — | — | WO | disclosed |