SCHEMBL244830

SCHEMBL244830

CC(C)(C)[N+]([O-])=Cc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.59
ALDH1A1 P00352 5/20 0.49
KMT2A Q03164 1/20 0.49
G6PD P11413 2/20 0.42
GAA P10253 2/20 0.42
POLB P06746 1/20 0.42
FBP1 P09467 4/20 0.39
MAPT P10636 3/20 0.38
TSHR P16473 2/20 0.38
ALOX15 P16050 1/20 0.38
RECQL P46063 1/20 0.38
HSD17B10 Q99714 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6260317 1.00 TDP1 (0.59) TDP1ALDH1A1KMT2AG6PDGAA
SCHEMBL267779 1.00 TDP1 (0.59) TDP1ALDH1A1KMT2AG6PDGAA
Hydrogen Sulfide SCHEMBL28326251 0.98 TDP1 (0.58) TDP1ALDH1A1KMT2AG6PDGAA
Sulfuric Acid SCHEMBL27546343 0.89 TDP1 (0.54) TDP1ALDH1A1KMT2AG6PDGAA
SCHEMBL5711161 0.81 TDP1 (0.42) TDP1ALDH1A1KMT2AGAAMAPT
SCHEMBL15216491 0.80 FBP1 (0.44) TDP1ALDH1A1KMT2AGAAFBP1
SCHEMBL28552488 0.80 FBP1 (0.44) TDP1ALDH1A1KMT2AGAAFBP1
SCHEMBL4018127 0.79 TDP1 (0.53) TDP1ALDH1A1KMT2AG6PDGAA
SCHEMBL29136456 0.79 TDP1 (0.46) TDP1ALDH1A1KMT2AG6PDFBP1
SCHEMBL4958358 0.78 MAPT (0.48) TDP1ALDH1A1KMT2AGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1626 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12364732-B2 Systems and methods for treatment of hearing using dihexa TRANSDERMAL BIOTECHNOLOGY, INC. (US) 2025-07-22 US claimed
US-20240424050-A1 SYSTEMS AND METHODS FOR TREATMENT OF HEARING USING DIHEXA TRANSDERMAL BIOTECHNOLOGY, INC. (US) 2024-12-26 US claimed
EP-4453001-A2 DLL3 BINDING PEPTIDES AND USES THEREOF AMGEN INC. (US) 2024-10-30 EP claimed
CN-118852028-A Nitrone pyrimidine ring compound and preparation method thereof 南京工业大学 2024-10-29 CN claimed
CN-118791423-A Polyhydroxy imine sugar compound with alpha-glucosidase inhibitory activity and preparation method thereof 中国科学院成都生物研究所 2024-10-18 CN claimed
CN-118755113-A Preparation process of low molecular weight fluoropolymer 江苏天问新材料科技有限公司 2024-10-11 CN claimed
CN-118591771-A Initiator composition, negative photosensitive resin composition, method for producing pattern cured film, and insulating film 徐州博康信息化学品有限公司 2024-09-03 CN claimed
CN-118393812-B Patterning composition, patterning film, patterning substrate, semiconductor device, and method of manufacturing the same 珠海基石科技有限公司 2024-08-30 CN claimed
CN-118525249-A Latent curing agent, low-temperature-cured photosensitive resin composition, method for producing pattern-cured film, and insulating film 徐州博康信息化学品有限公司 2024-08-20 CN claimed
CN-118393812-A Patterning composition, patterning film, patterning substrate, semiconductor device, and method of manufacturing the same 珠海基石科技有限公司 2024-07-26 CN claimed
US-5622994-A NITRONE DERIVATIVES OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) 1997-04-22 US claimed
US-5610699-A Photoreceptor cleaning apparatus and method XEROX CORPORATION (US) 1997-03-11 US claimed
EP-0665003-B1 The use of a spin acceptor in a cosmetic or dermatological composition OREAL (FR) 1996-08-28 EP claimed
US-5550272-A Method for hydrosilating unsaturated monomers GENERAL ELECTRIC COMPANY (US) 1996-08-27 US claimed
EP-0665003-A1 The use of a spin acceptor in a cosmetic on dermatological composition L'OREAL (FR) 1995-08-02 EP claimed
EP-0327263-B1 Hair growth stimulation with nitroxide and other radicals PROCTOR PETER H (US) 1994-09-07 EP claimed
US-5106723-A Contrast enhancement layer compositions, alkylnitrones, and use MICROSI, INC. (US) 1992-04-21 US claimed
US-5002993-A Contrast enhancement layer compositions, alkylnitrones, and use MICROSI, INC. (US) 1991-03-26 US claimed
WO-1988005653-A1 TOPICAL COMPOSITION FOR STIMULATING HAIR GROWTH WITH STABLE FREE RADICALS PROCTOR PETER H (US) 1988-08-11 WO claimed
US-3988229-A Stabilized photopolymerizable polymeric compositions containing a photoinitiator and a nitrone derivative EASTMAN KODAK COMPANY (US) 1976-10-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12364732-B2 Systems and methods for treatment of hearing using dihexa PRPH, LTA, SPAST TDP1 424/4885ALDH1A1 2405/4885KMT2A 2758/4885
US-20240424050-A1 SYSTEMS AND METHODS FOR TREATMENT OF HEARING USING DIHEXA PRPH, LTA, SPAST TDP1 424/4885ALDH1A1 2405/4885KMT2A 2758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.