Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | PPM1B | O75688 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9766250 | 0.80 | MEN1 (0.33) | — | |
| SCHEMBL21694945 | 0.75 | PPM1B (0.41) | CYP2C19CHRNB2CHRNA4PPM1BPTPN1 | |
| SCHEMBL3281202 | 0.73 | CHRM2 (0.40) | CYP2C19CHRNB2CHRNA4 | |
| SCHEMBL9551372 | 0.71 | CHRM2 (0.43) | CYP2C19CHRNB2CHRNA4 | |
| SCHEMBL1859619 | 0.70 | CYP1A2 (0.48) | CYP2C19CHRNB2CHRNA4 | |
| SCHEMBL12631398 | 0.70 | CYP1A2 (0.48) | CYP2C19CHRNB2CHRNA4 | |
| SCHEMBL1857022 | 0.70 | CYP1A2 (0.48) | CYP2C19CHRNB2CHRNA4 | |
| SCHEMBL1577524 | 0.69 | CYP2C19 (0.44) | CYP2C19CHRNB2CHRNA4PPM1BPTPN1 | |
| SCHEMBL2701193 | 0.68 | CHRM2 (0.42) | CYP2C19CHRNB2CHRNA4PPM1BPTPN1 | |
| SCHEMBL16672190 | 0.68 | CHRNB2 (0.43) | CYP2C19CHRNB2CHRNA4SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220169580-A1 | METHODS OF CARBON-CARBON BOND FRAGMENTATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220169580-A1 | METHODS OF CARBON-CARBON BOND FRAGMENTATION | CYCS, COX6C, COXFA4L2 | CYP2C19 3957/4885CHRNB2 2207/4885CHRNA4 3509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.