Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | RECQL | P46063 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29055118 | 0.96 | ALDH1A1 (0.42) | MEN1KMT2AL3MBTL1ALDH1A1POLB | |
| SCHEMBL24485260 | 0.94 | MEN1 (0.36) | MEN1KMT2AL3MBTL1ALDH1A1POLB | |
| SCHEMBL29712895 | 0.93 | MEN1 (0.39) | MEN1KMT2AL3MBTL1ALDH1A1POLB | |
| SCHEMBL29055119 | 0.93 | MEN1 (0.39) | MEN1KMT2AL3MBTL1ALDH1A1POLB | |
| SCHEMBL28862818 | 0.90 | MAPK1 (0.39) | MEN1KMT2AL3MBTL1ALDH1A1POLB | |
| SCHEMBL29712900 | 0.90 | MEN1 (0.40) | MEN1KMT2AL3MBTL1ALDH1A1POLB | |
| SCHEMBL29055100 | 0.90 | MEN1 (0.40) | MEN1KMT2AL3MBTL1ALDH1A1POLB | |
| SCHEMBL29055123 | 0.89 | CA1 (0.35) | MEN1KMT2AALDH1A1POLBGAA | |
| SCHEMBL29055115 | 0.89 | CA1 (0.35) | MEN1KMT2A | |
| SCHEMBL29055114 | 0.89 | CA1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240124432-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2024-04-18 | — | — | US | disclosed |
| EP-4250928-A1 | HERBICIDAL COMPOUNDS | Syngenta Crop Protection AG (CH) | 2023-10-04 | — | — | EP | disclosed |
| CN-116568673-A | Herbicidal compounds | 先正达农作物保护股份公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-114644622-B | Isoxazoline-containing pyridine biphenyl compound and preparation method and application thereof | 山东省联合农药工业有限公司 | 2022-10-18 | — | — | CN | disclosed |
| WO-2022112072-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-06-02 | — | — | WO | disclosed |
| WO-2022112072-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-06-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240124432-A1 | HERBICIDAL COMPOUNDS | DDT, ACHE, GSTO1 | MEN1 3365/4885KMT2A 1038/4885L3MBTL1 1508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.