Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRB2 | P62993 | 1/20 | 0.47 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.43 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | NTSR2 | O95665 | 3/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 4/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | RAMP3 | O60896 | 3/20 | 0.39 |
| ▸ | CALCR | P30988 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24485294 | 1.00 | GRB2 (0.47) | GRB2NMUR2NMUR1PLK1NTSR2 | |
| SCHEMBL29629002 | 0.92 | GRB2 (0.50) | GRB2NMUR2NMUR1PLK1NTSR2 | |
| SCHEMBL30962076 | 0.88 | GRB2 (0.50) | GRB2NMUR2NMUR1NTSR2NTSR1 | |
| SCHEMBL30010846 | 0.86 | NMUR2 (0.54) | NMUR2NMUR1CAPN1RAMP3CALCR | |
| SCHEMBL24485494 | 0.84 | GRB2 (0.49) | GRB2NMUR2NMUR1MAPK8MAPK9 | |
| SCHEMBL29701311 | 0.83 | OPRM1 (0.46) | GRB2NMUR2NMUR1PLK1NTSR2 | |
| SCHEMBL29379382 | 0.83 | NTSR2 (0.48) | NMUR2NMUR1PLK1NTSR2NTSR1 | |
| SCHEMBL29608389 | 0.83 | OPRM1 (0.51) | GRB2NMUR2NMUR1PLK1NTSR2 | |
| SCHEMBL31106416 | 0.82 | NTSR2 (0.49) | GRB2NTSR2NTSR1CAPN1SORT1 | |
| SCHEMBL30133583 | 0.82 | GRB2 (0.47) | GRB2NMUR2NMUR1NTSR2NTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220169677-A1 | NRP-1 BINDING INHIBITORY PEPTIDES AND USES THEREOF | UNIVERSITÉ PARIS CITÉ (FR) | 2022-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220169677-A1 | NRP-1 BINDING INHIBITORY PEPTIDES AND USES THEREOF | NRP1, KDR, FLT1 | GRB2 552/4885NMUR2 482/4885NMUR1 197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.