Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRB2 | P62993 | 1/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 6/20 | 0.47 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.47 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.47 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | RAMP3 | O60896 | 3/20 | 0.43 |
| ▸ | CALCR | P30988 | 3/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30962076 | 0.94 | GRB2 (0.50) | GRB2CAPN1NMUR2NMUR1NTSR2 | |
| SCHEMBL24485294 | 0.92 | GRB2 (0.47) | GRB2CAPN1NMUR2NMUR1NTSR2 | |
| SCHEMBL24485295 | 0.92 | GRB2 (0.47) | GRB2CAPN1NMUR2NMUR1NTSR2 | |
| SCHEMBL29379382 | 0.91 | NTSR2 (0.48) | NMUR2NMUR1NTSR2NTSR1OPRM1 | |
| SCHEMBL29701311 | 0.91 | OPRM1 (0.46) | GRB2NMUR2NMUR1NTSR2NTSR1 | |
| SCHEMBL30010846 | 0.90 | NMUR2 (0.54) | CAPN1NMUR2NMUR1RAMP3CALCR | |
| SCHEMBL30567782 | 0.89 | RAMP3 (0.47) | GRB2NMUR2NMUR1OPRM1OPRK1 | |
| SCHEMBL31509204 | 0.88 | NTSR2 (0.45) | GRB2CAPN1NMUR2NMUR1NTSR2 | |
| SCHEMBL31031506 | 0.88 | NTSR2 (0.48) | CAPN1NMUR2NMUR1NTSR2NTSR1 | |
| SCHEMBL24485494 | 0.87 | GRB2 (0.49) | GRB2NMUR2NMUR1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12590122-B2 | NRP-1 binding inhibitory peptides and uses thereof | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2026-03-31 | — | — | US | disclosed |
| US-20220169677-A1 | NRP-1 BINDING INHIBITORY PEPTIDES AND USES THEREOF | UNIVERSITÉ PARIS CITÉ (FR) | 2022-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12590122-B2 | NRP-1 binding inhibitory peptides and uses thereof | NRP1, FLT1, KDR | GRB2 543/4885CAPN1 2238/4885NMUR2 1241/4885 |
| US-20220169677-A1 | NRP-1 BINDING INHIBITORY PEPTIDES AND USES THEREOF | NRP1, KDR, FLT1 | GRB2 552/4885CAPN1 3328/4885NMUR2 482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.