Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4489356 | 0.82 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2MAPTHPGDLMNA | |
| SCHEMBL15331186 | 0.80 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MAPTHPGDLMNA | |
| SCHEMBL20234288 | 0.80 | L3MBTL1 (0.51) | MAPTHPGDHDAC1NPC1RAB9A | |
| SCHEMBL20234287 | 0.79 | L3MBTL1 (0.50) | MAPTHPGDHDAC1NPC1RAB9A | |
| SCHEMBL20234277 | 0.79 | L3MBTL1 (0.50) | MAPTHPGDHDAC1NPC1RAB9A | |
| SCHEMBL20234291 | 0.79 | L3MBTL1 (0.50) | MAPTHPGDHDAC1NPC1RAB9A | |
| SCHEMBL20234271 | 0.79 | L3MBTL1 (0.50) | MAPTHPGDHDAC1NPC1RAB9A | |
| SCHEMBL20325853 | 0.77 | RAB9A (0.51) | SMN1; SMN2MAPTLMNAHDAC1HDAC2 | |
| SCHEMBL8371513 | 0.75 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2MAPTHPGDLMNA | |
| SCHEMBL20234266 | 0.75 | MEN1 (0.47) | ALDH1A1MAPTHPGDRARBMMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11352351-B2 | Compounds and methods for the targeted degradation of androgen receptor | ARVINAS OPERATIONS, INC. (US) | 2022-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352351-B2 | Compounds and methods for the targeted degradation of androgen receptor | AR, ESRRA, MDM2 | ALDH1A1 460/4885SMN1; SMN2 4783/4885MAPT 3645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.