Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
| ▸ | CEL | P19835 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4012084 | 0.66 | — | — | |
| SCHEMBL6846074 | 0.66 | — | — | |
| SCHEMBL3116028 | 0.66 | — | — | |
| SCHEMBL21646523 | 0.65 | HRH3 (0.40) | HRH4 | |
| SCHEMBL1524531 | 0.61 | HRH4 (0.39) | HTR3AHRH4DAOLTA4HCEL | |
| SCHEMBL1524971 | 0.60 | DAO (0.37) | HTR3AHRH4DAOCEL | |
| Hydrochloric Acid SCHEMBL3680479 | 0.59 | HTR3A (0.32) | HTR3AHRH4DAO | |
| SCHEMBL1524841 | 0.59 | ALDH1A1 (0.40) | HTR3AHRH4DAOCEL | |
| SCHEMBL5054800 | 0.59 | TAAR1 (0.33) | — | |
| SCHEMBL217366 | 0.59 | HTR3A (0.34) | HTR3AHRH4DAOCEL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364982-A1 | Spiro-piperidine compounds as chemokine receptor antagonists and medicinal use thereof | ONO Pharmaceutical Co., Ltd. (JP) | 2011-09-14 | — | — | EP | disclosed |