Sugi Predict

Sugi Predict / Compounds / SCHEMBL2448733

SCHEMBL2448733

SCHEMBL2448733

C=Cc1ccccc1Cc1ccc(Cl)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.45
▸ TBXA2R P21731 3/20 0.40
▸ PTGER3 P43115 3/20 0.40
▸ PTGER2 P43116 3/20 0.40
▸ PTGDR Q13258 3/20 0.40
▸ PTGFR P43088 2/20 0.40
▸ PTGIR P43119 2/20 0.40
▸ PTGER1 P34995 1/20 0.40
▸ PTGER4 P35408 1/20 0.40
▸ MEN1 O00255 3/20 0.40
▸ KMT2A Q03164 3/20 0.40
▸ MAPT P10636 2/20 0.40
▸ CYP3A4 P08684 2/20 0.40
▸ HPGD P15428 1/20 0.40
▸ ALOX15 P16050 1/20 0.40
▸ HIF1A Q16665 1/20 0.40
▸ HSD17B10 Q99714 1/20 0.40
▸ SLC5A1 P13866 1/20 0.38
▸ SLC5A2 P31639 1/20 0.38
▸ L3MBTL1 Q9Y468 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL163961 0.84 CALM1 (0.46) ALDH1A1TBXA2RPTGER3PTGER2PTGDR
SCHEMBL28682859 0.83 SLC5A1 (0.43) ALDH1A1TBXA2RPTGER3PTGER2PTGDR
SCHEMBL11464004 0.83 MEN1 (0.44) ALDH1A1TBXA2RPTGER3PTGER2PTGDR
SCHEMBL20767519 0.81 SLC5A1 (0.39) ALDH1A1TBXA2RPTGER3PTGER2PTGDR
SCHEMBL454171 0.81 ALDH1A1 (0.46) ALDH1A1TBXA2RPTGER3PTGER2PTGDR
SCHEMBL21990472 0.81 TBXA2R (0.37) ALDH1A1TBXA2RPTGER3PTGER2PTGDR
SCHEMBL20767518 0.81 PNMT (0.43) ALDH1A1TBXA2RPTGER3PTGER2PTGDR
SCHEMBL28430403 0.80 PTGDR (0.46) ALDH1A1TBXA2RPTGER3PTGER2PTGDR
SCHEMBL50299 0.80 ALDH1A1 (0.48) ALDH1A1TBXA2RPTGER3PTGER2PTGDR
SCHEMBL19179321 0.77 ALDH1A1 (0.52) ALDH1A1TBXA2RPTGER3PTGER2PTGDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107382884-A Synthesis method of beta-iodo-N-alkoxy benzotriazole compound 浙江工业大学 2017-11-24 — — CN claimed
CN-107382821-A Synthesis method of beta-iodine-N-alkoxy amine compound 浙江工业大学 2017-11-24 — — CN claimed
CN-106187858-A A kind of synthetic method of β iodine N alkoxyamine compounds 浙江工业大学 2016-12-07 — — CN claimed
US-20250257027-A1 SECOND GENERATION GRP94-SELECTIVE INHIBITORS UNIVERSITY OF KANSAS (US) 2025-08-14 — — US disclosed
US-12269798-B2 Second generation GRP94-selective inhibitors UNIVERSITY OF KANSAS (US) 2025-04-08 — — US disclosed
US-11795610-B2 Coating materials, and personal protective clothing items coated with the coating materials BATTELLE MEMORIAL INSTITUTE (US) 2023-10-24 — — US disclosed
US-20220074128-A1 COATING MATERIALS, AND PERSONAL PROTECTIVE CLOTHING ITEMS COATED WITH THE COATING MATERIALS BATTELLE MEMORIAL INSTITUTE 2022-03-10 — — US disclosed
US-11220781-B2 Coating materials, and personal protective clothing items coated with the coating materials BATTELLE MEMORIAL INSTITUTE (US) 2022-01-11 — — US disclosed
EP-3464708-B1 COATING MATERIALS, AND PERSONAL PROTECTIVE CLOTHING ITEMS COATED WITH THE COATING MATERIALS BATTELLE MEMORIAL INSTITUTE (US) 2021-10-06 — — EP disclosed
US-20210300872-A1 SECOND GENERATION GRP94-SELECTIVE INHIBITORS UNIVERSITY OF KANSAS 2021-09-30 — — US disclosed
US-20210300872-A1 SECOND GENERATION GRP94-SELECTIVE INHIBITORS UNIVERSITY OF KANSAS 2021-09-30 — — US disclosed
EP-2392623-B1 Electrically conductive coating composition BATTELLE MEMORIAL INSTITUTE (US) 2013-09-18 — — EP disclosed
EP-2392623-A2 Electrically conductive coating composition BATTELLE MEMORIAL INSTITUTE (US) 2011-12-07 — — EP disclosed
EP-2069440-B1 ELECTRICALLY CONDUCTIVE COATING COMPOSITION BATTELLE MEMORIAL INSTITUTE (US) 2011-09-28 — — EP disclosed
US-20100126981-A1 ELECTRICALLY CONDUCTIVE COATING COMPOSITION BATTELLE MEMORIAL INSTITUTE (US) 2010-05-27 — — US disclosed
EP-2069440-A2 ELECTRICALLY CONDUCTIVE COATING COMPOSITION BATTELLE MEMORIAL INSTITUTE (US) 2009-06-17 — — EP disclosed
WO-2008085550-A2 ELECTRICALLY CONDUCTIVE COATING COMPOSITION BATTELLE MEMORIAL INSTITUTE (US) 2008-07-17 — — WO disclosed
EP-0807659-B1 Polyolefin-based composite material and production process therefor SHOWA DENKO KK (JP) 1999-11-03 — — EP disclosed
US-5939184-A GRAFT OR BLOCK COPOLYMER CONTAINING UNSATURATED CARBOXYLIC ACID OR DERIVATIVES AND LIPOPHILIC INTERSTRATIFIED COMPOUND WITH A TETRAALKYLAMMONIUM CATION INSERTED IN A SWELLABLE STRATIFORM SILICATE; IMPACT STRENGTH, HEAT RESISTANCE SHOWA DENKO K.K. (JP) 1999-08-17 — — US disclosed
EP-0807659-A1 Polyolefin-based composite material and production process therefor SHOWA DENKO KABUSHIKI KAISHA (JP) 1997-11-19 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12269798-B2 Second generation GRP94-selective inhibitors HSP90B1, HSP90AB2P, HSPE1 ALDH1A1 3322/4885TBXA2R 1600/4885PTGER3 1360/4885
US-20210300872-A1 SECOND GENERATION GRP94-SELECTIVE INHIBITORS HSP90B1, HSP90AB2P, HSPE1 ALDH1A1 3322/4885TBXA2R 1600/4885PTGER3 1360/4885
US-20250257027-A1 SECOND GENERATION GRP94-SELECTIVE INHIBITORS HSP90B1, HSP90AB2P, HSPE1 ALDH1A1 3289/4885TBXA2R 1526/4885PTGER3 1250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.