Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | GLA | P06280 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.55 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL27715747 | 0.92 | ALDH1A1 (0.47) | LMNAKMT2AALDH1A1HPGDGAA | |
| Quinoline SCHEMBL27619023 | 0.89 | ALDH1A1 (0.50) | LMNAKMT2AALDH1A1HPGDGAA | |
| SCHEMBL27953099 | 0.86 | LMNA (0.49) | LMNAKMT2AALDH1A1HPGDGAA | |
| SCHEMBL30044538 | 0.81 | ALDH1A1 (0.55) | LMNAKMT2AALDH1A1HPGDGAA | |
| SCHEMBL291404 | 0.81 | ALDH1A1 (0.55) | LMNAKMT2AALDH1A1HPGDGAA | |
| SCHEMBL28369826 | 0.81 | KDM4E (0.55) | LMNAKMT2AALDH1A1HPGDGAA | |
| SCHEMBL6008038 | 0.81 | KDM4E (0.55) | LMNAKMT2AALDH1A1HPGDGAA | |
| SCHEMBL738321 | 0.81 | ALDH1A1 (0.55) | LMNAKMT2AALDH1A1HPGDGAA | |
| SCHEMBL27568818 | 0.81 | NPC1 (0.40) | LMNAKMT2AALDH1A1HPGDGAA | |
| Hydrochloric Acid SCHEMBL9634743 | 0.80 | ALDH1A1 (0.53) | LMNAKMT2AALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4378936-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | Hinova Pharmaceuticals Inc. (CN) | 2024-06-05 | — | — | EP | claimed |
| CN-105287540-A | Application of 7'-methyl-8'-chloro-2-hydroxy benzo [c] pyrido [4,3,2-mn] acridine-8-ketone in angiogenesis inhibition drug | YANG YANG | 2016-02-03 | — | — | CN | claimed |
| CN-105250281-A | Application of 7'-methyl-8'-bromo-metoxybenzeneo[c]pyridineo[4,3,2-mn]acridine-8-one in angiogenesis inhibiting drugs | YANG YANG | 2016-01-20 | — | — | CN | claimed |
| CN-105250282-A | Application of 7'-ethyl-8'-chlorine-3-hydroxyl benzo [c] pyridine [4,3,2-mn] acridine-8-ketone in angiogenesis inhibiting drug | YANG YANG | 2016-01-20 | — | — | CN | claimed |
| CN-102321084-B | Method for synthesizing benzo[c]pyridine[4,3,2-mn]acridine-8-one | NANJING UNIVERSITY OF TECHNOLOGY | 2013-03-13 | — | — | CN | claimed |
| CN-102321084-A | Method for synthesizing benzo[c]pyridine[4,3,2-mn]acridine-8-one | NANJING UNIVERSITY OF TECHNOLOGY | 2012-01-18 | — | — | CN | claimed |
| EP-1433785-A1 | Agents for the coloration of keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-06-30 | — | — | EP | claimed |
| US-6414152-B1 | COMPOUND CAPABLE OF UNDERGOING LIGHT EMITTING REACTION IN PRESENCE OF DILUTE SOLUTION OF SODIUM HYDROXIDE AND HYDROGEN PEROXIDE, COMPRISING ACRIDINIUM CARBONYL MOIETY SUBSTITUTED WITH ARYL MOIETY HAVING ATTACHED REACTIVE GROUP | UNIVERSITY OF WALES COLLEGE OF MEDICINE OF HEATH PARK (GB) | 2002-07-02 | — | — | US | claimed |
| WO-1997027179-A2 | ANTIRETROVIRAL BASES | NOVARTIS AG (CH) | 1997-07-31 | — | — | WO | claimed |
| EP-4378936-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | Hinova Pharmaceuticals Inc. (CN) | 2024-06-05 | — | — | EP | disclosed |
| US-20230096635-A1 | CROSS-LINKED POLYMERIC MATERIALS, METHODS OF THEIR PREPARATION AND USES THEREOF | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2023-03-30 | — | — | US | disclosed |
| CN-115835751-A | Organic light emitting diode and organic light emitting device including the same | 乐金显示有限公司 | 2023-03-21 | — | — | CN | disclosed |
| EP-4100459-A1 | CROSS-LINKED POLYMERIC MATERIALS, METHODS OF THEIR PREPARATION AND USES THEREOF | The University of British Columbia (CA) | 2022-12-14 | — | — | EP | disclosed |
| WO-2021155461-A1 | CROSS-LINKED POLYMERIC MATERIALS, METHODS OF THEIR PREPARATION AND USES THEREOF | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2021-08-12 | — | — | WO | disclosed |
| US-6242188-B1 | Sample processing to release nucleic acids for direct detection | APPLIED GENE TECHNOLOGIES, INC. | 2001-06-05 | — | — | US | disclosed |
| US-6239108-B1 | Cell adhesion inhibitors | BIOGEN, INC. | 2001-05-29 | — | — | US | disclosed |
| CN-1282332-A | Novel acronycine compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-01-31 | — | — | CN | disclosed |
| US-5665606-A | Method for assaying a substance using a polyacridinium compound | KYOWA MEDEX CO., LTD. (JP) | 1997-09-09 | — | — | US | disclosed |
| WO-1997027179-A2 | ANTIRETROVIRAL BASES | NOVARTIS AG (CH) | 1997-07-31 | — | — | WO | disclosed |
| EP-0676641-A1 | Method for assaying a substance | KYOWA MEDEX CO., LTD. (JP) | 1995-10-11 | — | — | EP | disclosed |