Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | LMNA | P02545 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.47 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2448842 | 0.92 | LMNA (0.55) | ALDH1A1LMNAHPGDKMT2AKDM4E | |
| Quinoline SCHEMBL27619023 | 0.85 | ALDH1A1 (0.50) | ALDH1A1LMNAHPGDKMT2AKDM4E | |
| Pyridine SCHEMBL28099708 | 0.84 | ALDH1A1 (0.42) | ALDH1A1LMNAHPGDKMT2AKDM4E | |
| Pyridine SCHEMBL28166520 | 0.82 | CYP1A2 (0.50) | ALDH1A1LMNAHPGDKMT2AKDM4E | |
| SCHEMBL27953099 | 0.79 | LMNA (0.49) | ALDH1A1LMNAHPGDKMT2AKDM4E | |
| SCHEMBL27568818 | 0.78 | NPC1 (0.40) | ALDH1A1LMNAHPGDKMT2AKDM4E | |
| Acridine SCHEMBL5707074 | 0.77 | ALDH1A1 (0.71) | ALDH1A1LMNAHPGDKMT2AKDM4E | |
| Pyridine SCHEMBL28268794 | 0.76 | HPRT1 (0.45) | ALDH1A1LMNAHPGDKMT2APOLB | |
| SCHEMBL30044538 | 0.75 | ALDH1A1 (0.55) | ALDH1A1LMNAHPGDKMT2AKDM4E | |
| SCHEMBL28369826 | 0.75 | KDM4E (0.55) | ALDH1A1LMNAHPGDKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101076332-A | Pyrazole or triazole compounds and their use for the manufacture of a medicament for treating somatic mutation-related diseases | PTC THERAPEUTICS INC (US) | 2007-11-21 | — | — | CN | disclosed |