Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29633597 | 0.81 | ALDH1A1 (0.43) | TSHRHSD17B10LMNAHTTCYP3A4 | |
| SCHEMBL22946235 | 0.81 | ALDH1A1 (0.43) | TSHRHSD17B10LMNAHTTCYP3A4 | |
| SCHEMBL9303456 | 0.71 | ADORA3 (0.35) | TSHRHSD17B10LMNACYP3A4ALDH1A1 | |
| SCHEMBL28706149 | 0.69 | TDP1 (0.48) | TSHRHSD17B10HTTCYP3A4ALDH1A1 | |
| SCHEMBL31634962 | 0.69 | TDP1 (0.48) | TSHRHSD17B10HTTCYP3A4ALDH1A1 | |
| SCHEMBL29633557 | 0.68 | TSHR (0.44) | TSHRHSD17B10LMNAHTTCYP3A4 | |
| SCHEMBL16575395 | 0.67 | TSHR (0.44) | TSHRHSD17B10LMNAHTTCYP3A4 | |
| Ammonia Solution, Strong SCHEMBL28263808 | 0.66 | TSHR (0.57) | TSHRHSD17B10LMNAHTTCYP3A4 | |
| SCHEMBL31634964 | 0.66 | TDP1 (0.45) | TSHRHSD17B10LMNAHTTCYP3A4 | |
| SCHEMBL28719326 | 0.66 | TDP1 (0.45) | TSHRHSD17B10LMNAHTTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4008405-A1 | UREA COMPOUND FOR ANTAGONIZING LPA1 RECEPTOR | Taisho Pharmaceutical Co., Ltd. (JP) | 2022-06-08 | — | — | EP | disclosed |